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[长期护理中的药物供应与多重用药:可能干预措施概述及有效概念问题]

[Medication supply and polypharmacy in long-term care : An overview of possible interventions and the question of a functioning concept].

作者信息

Graeb Fabian, Berger Bianca, Alf Frank, Reiber Petra, Essig Gundula, Wolke Reinhold

机构信息

Institut für Gesundheits- und Pflegewissenschaften, Hochschule Esslingen, Flandernstraße 101, 73732, Esslingen, Deutschland.

出版信息

Z Gerontol Geriatr. 2025 May;58(3):214-219. doi: 10.1007/s00391-024-02340-1. Epub 2024 Aug 13.

DOI:10.1007/s00391-024-02340-1
PMID:39136716
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12048413/
Abstract

BACKGROUND

Polypharmacy and the resulting problems lead to considerable consequences for those affected. There are also considerable problems with the medication management.

OBJECTIVE

Which interventions and programs for optimizing the supply of medication are available for nursing homes and which implementation problems can be expected?

MATERIAL AND METHOD

A literature search was carried out for interventional studies in nursing homes in Germany, with a focus on improving medication safety.

RESULTS

A total of six programs were identified for which evaluation results are available. Despite a mostly multimodal approach with several pillars of intervention (e.g., medication reviews, further education and training, development of aids), the results are largely disappointing. The effects on the number of prescriptions in general, specific medication groups or outcome parameters such as hospital admissions could only be shown in one study, whereby, selection bias could also be at least partly responsible for this. Interdisciplinary collaboration and the implementation of medication recommendations formulated in reviews by the responsible physicians are the main problem areas. At the same time, too little attention is paid to the central role of nurses in the entire process and they are not actively promoted enough. This could be one of the reasons for the difficulties in implementation in practice.

CONCLUSION

There are nearly no significant changes as a result of the interventions implemented in the studies reviewed. In particular, interprofessional cooperation, especially the skills of nurses and the reluctance on the part of physicians, should probably be given more attention.

摘要

背景

多重用药及其引发的问题给患者带来了相当严重的后果。药物管理也存在诸多问题。

目的

养老院可采用哪些干预措施和方案来优化药物供应,可能会遇到哪些实施问题?

材料与方法

对德国养老院的干预性研究进行文献检索,重点关注提高用药安全性。

结果

共确定了六个有评估结果的项目。尽管大多采用多模式方法,有多个干预支柱(如药物审查、继续教育与培训、辅助工具开发),但结果大多令人失望。只有一项研究显示了对总体处方数量、特定药物组或诸如住院等结果参数的影响,不过,选择偏倚可能至少部分导致了这一结果。跨学科合作以及负责医生在审查中制定的用药建议的实施是主要问题领域。与此同时,整个过程中护士的核心作用未得到足够重视,对其积极性的调动也不够。这可能是实际实施困难的原因之一。

结论

在所审查的研究中实施的干预措施几乎没有带来显著变化。特别是跨专业合作,尤其是护士的技能以及医生的不情愿态度,可能应得到更多关注。

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本文引用的文献

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The role of qualification and quality management in the prescription of antipsychotics and potentially inappropriate medication (PIM) in nursing home residents in Germany: results of the HIOPP-3-iTBX study.在德国,护理院居民抗精神病药物和潜在不适当药物(PIM)处方中的资格和质量管理的作用:HIOPP-3-iTBX 研究的结果。
Aging Clin Exp Res. 2023 Oct;35(10):2227-2235. doi: 10.1007/s40520-023-02513-9. Epub 2023 Aug 7.
2
Optimising prescribing in older adults with multimorbidity and polypharmacy in primary care (OPTICA): cluster randomised clinical trial.优化初级保健中老年多病共存和多种药物治疗患者的处方(OPTICA): 集群随机临床试验。
BMJ. 2023 May 24;381:e074054. doi: 10.1136/bmj-2022-074054.
3
Drug-drug interactions in nursing home residents: analysis from the COME-ON trial.疗养院居民中的药物相互作用:来自COME-ON试验的分析。
Age Ageing. 2023 Jan 8;52(1). doi: 10.1093/ageing/afac278.
4
[Estimation of the risk of drug-related problems in nursing home residents : A retrospective analysis of routine data].[养老院居民药物相关问题风险的评估:常规数据的回顾性分析]
Z Gerontol Geriatr. 2023 Dec;56(8):673-678. doi: 10.1007/s00391-022-02152-1. Epub 2022 Dec 28.
5
Drug Safety for Nursing-Home Residents-Findings of a Pragmatic, Cluster-Randomized, Controlled Intervention Trialin 44 Nursing Homes.《养老院居民的药物安全 - 一项在 44 家养老院开展的实用、集群随机、对照干预试验的研究结果》。
Dtsch Arztebl Int. 2021 Oct 22;118(42):705-712. doi: 10.3238/arztebl.m2021.0297.
6
Polypharmacy in older adults: a narrative review of definitions, epidemiology and consequences.老年人多药治疗:定义、流行病学和后果的叙述性综述。
Eur Geriatr Med. 2021 Jun;12(3):443-452. doi: 10.1007/s41999-021-00479-3. Epub 2021 Mar 10.
7
[Identification of polypharmacy-associated risks among nursing home residents].[疗养院居民中多重用药相关风险的识别]
Z Gerontol Geriatr. 2022 May;55(3):231-238. doi: 10.1007/s00391-021-01850-6. Epub 2021 Feb 11.
8
Polypharmacy is a risk factor for hospital admission due to a fall: evidence from the English Longitudinal Study of Ageing.药物滥用是因跌倒而住院的一个风险因素:来自英国老龄化纵向研究的证据。
BMC Public Health. 2020 Nov 26;20(1):1804. doi: 10.1186/s12889-020-09920-x.
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An Algorithm for Comprehensive Medication Management in Nursing Homes: Results of the AMBER Project.养老院综合药物管理算法:琥珀项目的结果。
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Gesundheitswesen. 2020 Jan;82(1):14-22. doi: 10.1055/a-1071-7911. Epub 2020 Jan 21.