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光学与磁刺激联合应用于难愈性创面的效果:真实世界证据病例系列研究。

Effects of concurrent optical and magnetic stimulation in hard-to-heal wounds: a real-world evidence case series.

机构信息

Expertise Center of Wound Care, Oosterhout, the Netherlands.

Stichting Mijzo, Waalwijk, the Netherlands.

出版信息

J Wound Care. 2024 Aug 2;33(8):560-568. doi: 10.12968/jowc.2024.0133.

DOI:10.12968/jowc.2024.0133
PMID:39137251
Abstract

OBJECTIVE

This work explores concurrent optical and magnetic stimulation (COMS) effects on hard-to-heal wounds in real-world settings.

METHOD

In this case series, participants received COMS 1-3 times per week for up to 12 weeks alongside standard wound care.

RESULTS

A total of 27 patients (18 female and nine male) were included. Mean age was 72 years. Participants' wounds that were unresponsive to standard wound care included: venous leg ulcers (VLUs, n=13); mixed leg ulcers (MLUs, n=4); diabetic foot ulcers (DFUs, n=1); pressure ulcers (PUs, n=5); and traumatic wounds (TWs, n=4). On average, COMS was applied twice a week, resulting in an overall mean wound area reduction of 69%. In 24 participants, COMS was used primarily to achieve wound closure by the end of the 12-week period, of which: 12 were classified as complete wound closure (50%; VLUs=8, PUs=3 and TW=1); four as likely-to-heal (17%; VLUs=2 and MLUs=2); four as 'improved' (17%; MLU=1, DFU=1 and TWs=2); and four as 'non-responding' (17%; VLUs=3 and MLU=1). The best results were achieved in PUs and VLUs (respectively 100% and 62% categorised as completely healed). When used in participants where its purpose was other than that of achieving wound closure, COMS was successfully used to debride two PUs, and for wound bed preparation in one TW.

CONCLUSION

In this case series, COMS showed positive effects and appeared to be beneficial in healing different types of hard-to-heal wounds in community health and homecare settings. Novel COMS therapy aspects emerged: (1) positive outcomes for PU and VLU treatment; (2) COMS as a potential debridement tool when sharp debridement is unfeasible; and (3) COMS as a promising method to prepare wound beds for subsequent skin grafting or skin replacement procedures.

摘要

目的

本研究旨在探讨真实环境下联合光磁刺激(COMS)对难愈合伤口的作用。

方法

在本病例系列研究中,患者在接受标准伤口护理的同时每周接受 1-3 次 COMS 治疗,疗程最多 12 周。

结果

共纳入 27 名患者(18 名女性,9 名男性),平均年龄 72 岁。对标准伤口护理无反应的患者伤口包括:静脉性下肢溃疡(venous leg ulcers,VLUs,n=13)、混合性下肢溃疡(mixed leg ulcers,MLUs,n=4)、糖尿病足溃疡(diabetic foot ulcers,DFUs,n=1)、压疮(pressure ulcers,PUs,n=5)和创伤性伤口(traumatic wounds,TWs,n=4)。COMS 平均每周应用 2 次,总体平均伤口面积减少 69%。在 24 名患者中,COMS 主要用于在 12 周结束时实现伤口闭合,其中:12 例患者被归类为完全愈合(50%;VLUs=8,PUs=3 和 TW=1);4 例可能愈合(17%;VLUs=2 和 MLUs=2);4 例“改善”(17%;MLU=1,DFU=1 和 TWs=2);4 例“无反应”(17%;VLUs=3 和 MLU=1)。PU 和 VLUs 的效果最好(分别为 100%和 62%归类为完全愈合)。当 COMS 用于非闭合伤口时,它成功地用于清创 2 例 PUs,并为 1 例 TW 准备伤口床。

结论

在本病例系列研究中,COMS 显示出积极的效果,并且似乎有利于社区卫生和家庭护理环境中不同类型的难愈合伤口的愈合。出现了新的 COMS 治疗方面:(1)PU 和 VLU 治疗的积极结果;(2)当无法进行锐性清创时,COMS 作为一种潜在的清创工具;(3)COMS 作为一种有前途的方法,为随后的植皮或皮肤替代手术准备伤口床。

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