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使用多模态伤口基质治疗各种难愈性伤口:病例系列监测。

The use of a multimodal wound matrix to treat a variety of hard-to-heal wounds: a case series surveillance.

机构信息

First Coast Cardiovascular Institute, Jacksonville, FL, US.

Kent State University College of Podiatric Medicine, Kent, OH, US.

出版信息

J Wound Care. 2024 Sep 1;33(Sup9):S27-S35. doi: 10.12968/jowc.2024.0135.

Abstract

OBJECTIVE

This case series examines the use of a multimodal wound matrix (MWM) trialled in a selection of clinical practice settings and on a variety of hard-to-heal wounds. The objective was to evaluate the effects of MWM and its performance in managing such wounds, regardless of clinical setting and ulcer type.

METHOD

Treatment of the MWM was conducted by independent wound care practitioners on wounds that were of >4 weeks duration. Treatment was once a week. Assessment was taken after four weeks and at week 12 of the study to assess percentage area reduction (PAR) compared to baseline measurements taken at the first treatment visit. Complete (100%) re-epithelialisation was also recorded.

RESULTS

A total of 63 wounds were treated with MWM, and ulcer types were grouped as: diabetic foot ulcers (n=21); venous leg ulcers (n=18); pressure injuries (n=10); and others (n=14). Of the wounds, 78% had 100% re-epithelialisation, with an average PAR of 57% at four weeks and 86% at 12 weeks. The average time to resolution for those wounds that closed was 7.9 weeks.

CONCLUSION

Results from this series of independent case studies support the application of MWM to potentially benefit healing in hard-to-heal wounds of different aetiologies of any duration and in a variety of clinical settings.

摘要

目的

本病例系列研究考察了多模态伤口基质(MWM)在一系列临床实践环境中以及各种难治性伤口上的应用。目的是评估 MWM 的效果及其在管理这些伤口方面的表现,无论临床环境和溃疡类型如何。

方法

由独立的伤口护理从业者对病程超过 4 周的伤口进行 MWM 治疗。每周治疗一次。在研究的第 4 周和第 12 周,与首次治疗就诊时的基线测量值相比,评估面积减少百分比(PAR),以评估疗效。还记录了完全(100%)再上皮化的情况。

结果

共有 63 个伤口接受了 MWM 治疗,溃疡类型分为:糖尿病足溃疡(n=21);静脉性腿部溃疡(n=18);压力性损伤(n=10);其他(n=14)。其中 78%的伤口实现了 100%的再上皮化,第 4 周时的平均 PAR 为 57%,第 12 周时的平均 PAR 为 86%。那些愈合的伤口平均愈合时间为 7.9 周。

结论

这些独立病例研究的结果支持应用 MWM 以潜在促进不同病因、任何病程的难治性伤口的愈合,并适用于各种临床环境。

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