Angulo Frederick J, Halsby Kate, Davidson Alexander, Ravikumar Saiganesh, Pilz Andreas, Stark James H, Moïsi Jennifer C
Vaccines and Antivirals Medical Affairs, Pfizer Vaccines, 500 Arcola Rd, Collegeville, PA 19426, USA.
Vaccines and Antivirals Medical Affairs, Pfizer Vaccines, London, United Kingdom.
Ticks Tick Borne Dis. 2024 Nov;15(6):102388. doi: 10.1016/j.ttbdis.2024.102388. Epub 2024 Aug 13.
The European Centre for Disease Prevention and Control (ECDC) defines a case of tick-borne encephalitis (TBE) as an infection by the TBE virus (TBEV) with clinical manifestations of central nervous system inflammation (e.g., meningitis, encephalitis). To better understand the TBE surveillance landscape, online searches were conducted to determine if cases of TBE, TBEV infection, acute meningitis or encephalitis, or viral meningitis or encephalitis were subject to statutory reporting in European countries in 2023. In countries with statutory reporting, notification responsibility and available information on surveillance-reported cases were determined. The number of TBE cases reported to ECDC were compared with the number of cases recorded in national surveillance reports. Of 44 countries of the Europe Region of the United Nations, 37 (84 %) mandated statutory reporting of cases of TBE, TBEV infection, or acute/viral meningitis/encephalitis. Twenty-six (87 %) of 30 countries with identified surveillance reports recorded TBE cases in 2020-2023. Of these countries, 17 (65 %) required TBE reporting by clinicians and laboratories, 5 (19 %) by clinicians only, and 4 (15 %) by laboratories only. Twenty-four countries reported on TBE cases to ECDC in 2020; however, surveillance for TBE in Europe is heterogeneous. Standardization of TBE surveillance would enhance the understanding of TBE disease burden in Europe.
欧洲疾病预防控制中心(ECDC)将蜱传脑炎(TBE)病例定义为由蜱传脑炎病毒(TBEV)感染引起的、具有中枢神经系统炎症临床表现(如脑膜炎、脑炎)的病例。为了更好地了解TBE的监测情况,我们进行了在线搜索,以确定2023年欧洲国家的TBE病例、TBEV感染病例、急性脑膜炎或脑炎病例,或病毒性脑膜炎或脑炎病例是否需要法定报告。在有法定报告要求的国家,确定了报告责任以及监测报告病例的可用信息。将向ECDC报告的TBE病例数与国家监测报告中记录的病例数进行了比较。在联合国欧洲区域的44个国家中,37个(84%)规定对TBE病例、TBEV感染病例或急性/病毒性脑膜炎/脑炎病例进行法定报告。在已确定有监测报告的30个国家中,有26个(87%)在2020 - 2023年记录了TBE病例。在这些国家中,17个(65%)要求临床医生和实验室报告TBE病例,5个(19%)仅要求临床医生报告,4个(15%)仅要求实验室报告。2020年有24个国家向ECDC报告了TBE病例;然而,欧洲对TBE的监测情况参差不齐。TBE监测的标准化将有助于加深对欧洲TBE疾病负担的了解。