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ICU 日记对危重症患者及其家属心理障碍和睡眠质量的影响:系统评价和荟萃分析。

Effects of ICU diaries on psychological disorders and sleep quality in critically ill patients and their family members: A systematic review and meta-analysis.

机构信息

Medical School of Nantong University, Nantong, 226001, China.

Affiliated Hospital of Nantong University, Nantong, 226001, China.

出版信息

Sleep Med. 2024 Oct;122:84-91. doi: 10.1016/j.sleep.2024.08.002. Epub 2024 Aug 8.

Abstract

BACKGROUND

The psychological health and sleep quality of intensive care unit (ICU) patients and their families have health implications, and greater attention should be devoted to developing effective interventions to address these concerns. Due to an increasing amount of evidence on ICU diary interventions, their comparative effectiveness should be evaluated.

AIMS

This systematic review and meta-analysis aimed to evaluate the effect of ICU diaries on psychological disorders and sleep quality in critically ill patients and on psychological disorders in their family members.

METHODS

The PubMed, Embase, Web of Science, Cochrane Library, China Biomedical Literature Database, China National Knowledge Network, Wanfang Database, and Weipu Chinese Journal databases were searched up to November 2023 to identify randomized controlled trials. We used the Cochrane Risk of Bias Tool for quality assessment, and we used Review Manager 5.4 software to conduct meta-analysis.

RESULTS

Eleven studies with a total of 1682 patients met the inclusion criteria.

PATIENTS

PTSD (7 studies, 1015 patients): OR 0.63 (95%CI 0.45-0.87), p = 0.005; Anxiety (6 studies, 546 patients): OR 0.52 (95%CI 0.22-1.27), p = 0.15; Depression (6 studies, 546 patients): OR 0.62 (95%CI 0.39-0.97), p = 0.04; sleep quality (2 studies, 203 patients): OR -3.97 (95%CI -7.71-0.23), p = 0.04. Family members: PTSD (2 studies, 652 patients): OR 0.81 (95%CI 0.37-1.79), p = 0.60; Anxiety (2 studies, 650 family members): OR 1.09 (95%CI 0.79-1.49), p = 0.62; Depression (2 studies, 650 patients): OR 1.03 (95%CI 0.71-1.50), p = 0.87. The pooled results of the meta-analysis showed that ICU diaries reduced the incidence of depression and post-traumatic stress disorder and improved sleep quality in patients, but had no significant effects on patients' anxiety status or family members' psychological disorders. Three of the included studies had a high quality, and the remaining eight studies had a moderate quality.

CONCLUSIONS

For patients, ICU diaries can improve their depression and post-traumatic stress disorder, improve sleep quality, but has no significant effect on anxiety; For family members, ICU diaries were not significant. Due to the existence of bias and the limited sample size, the results should be interpreted with caution. Researchers need to further elucidate the multidisciplinary collaborative process of diary-based treatment in ICUs and its impact on psychological disorders in family members. Furthermore, large-scale, multicentre, robust studies should be conducted in the future.

摘要

背景

重症监护病房(ICU)患者及其家属的心理健康和睡眠质量具有重要的健康意义,应更加关注开发有效的干预措施来解决这些问题。由于 ICU 日记干预措施的证据越来越多,应评估其比较效果。

目的

本系统评价和荟萃分析旨在评估 ICU 日记对危重病患者心理障碍和睡眠质量的影响,以及对其家属心理障碍的影响。

方法

检索PubMed、Embase、Web of Science、Cochrane 图书馆、中国生物医学文献数据库、中国国家知识网络、万方数据库和维普中文期刊数据库,截至 2023 年 11 月,以识别随机对照试验。我们使用 Cochrane 偏倚风险工具进行质量评估,并使用 Review Manager 5.4 软件进行荟萃分析。

结果

共有 11 项研究,总计 1682 名患者符合纳入标准。

患者

创伤后应激障碍(7 项研究,1015 名患者):OR 0.63(95%CI 0.45-0.87),p=0.005;焦虑(6 项研究,546 名患者):OR 0.52(95%CI 0.22-1.27),p=0.15;抑郁(6 项研究,546 名患者):OR 0.62(95%CI 0.39-0.97),p=0.04;睡眠质量(2 项研究,203 名患者):OR -3.97(95%CI -7.71-0.23),p=0.04。家属:创伤后应激障碍(2 项研究,652 名患者):OR 0.81(95%CI 0.37-1.79),p=0.60;焦虑(2 项研究,650 名家属):OR 1.09(95%CI 0.79-1.49),p=0.62;抑郁(2 项研究,650 名患者):OR 1.03(95%CI 0.71-1.50),p=0.87。荟萃分析的汇总结果表明,ICU 日记降低了患者抑郁和创伤后应激障碍的发生率,改善了睡眠质量,但对患者焦虑状况或家属心理障碍没有显著影响。纳入的 3 项研究质量较高,其余 8 项研究质量中等。

结论

对于患者,ICU 日记可以改善他们的抑郁和创伤后应激障碍,改善睡眠质量,但对焦虑没有显著影响;对于家属,ICU 日记没有显著影响。由于存在偏倚和样本量有限,结果应谨慎解释。研究人员需要进一步阐明 ICU 基于日记的治疗的多学科协作过程及其对家属心理障碍的影响。此外,未来需要进行更大规模、多中心、稳健的研究。

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