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在诊断为慢性精神分裂症和分裂情感障碍的患者样本中重新考察神经认知、自我挫败信念、体验性阴性症状与社会功能之间的关系。

Reexamination of the relationships among neurocognition, self-defeatist beliefs, experiential negative symptoms, and social functioning in a sample of patients diagnosed with chronic schizophrenia and schizoaffective disorder.

机构信息

Department of Educational Psychology and Counseling, National Tsing Hua University, 521 Nan-Da Road, Hsinchu City, 30014, Taiwan.

Department of General Psychiatry, Yuli Hospital, Ministry of Health and Welfare, Hualien County, Taiwan.

出版信息

BMC Psychiatry. 2024 Aug 13;24(1):559. doi: 10.1186/s12888-024-06003-8.

Abstract

PURPOSE

This study proposed and evaluated a theoretical model for exploring the relationships between neurocognition, self-defeatist beliefs, experiential negative symptoms, and social functioning in individuals with chronic schizophrenia.

METHOD

The study recruited 229 individuals given a diagnosis of schizophrenia and schizoaffective disorders from outpatient clinics and the day ward of a mental health hospital. After informed consent was obtained, the participants underwent assessments using the backward digit span, the digit symbol, and measures of self-defeatist beliefs, experiential negative symptoms, and social functioning. A structural equation model was applied to assess the fitness of the hypothesized model, with indices such as the goodness-of-fit index, comparative fit index, root mean square error of approximation, and standardized root mean square residual being used for model evaluation.

RESULTS

The hypothesized model had an adequate fit. The study findings indicated that neurocognition might indirectly influence self-defeatist beliefs through its effect on experiential negative symptoms. Contrary to expectations, the study did not observe a direct influence of neurocognition, self-defeatist beliefs, or negative symptoms on social functioning. The revised model revealed the role of experiential negative symptoms in mediating the association between neurocognition and social functioning. However, self-defeatist beliefs did not significantly affect social functioning.

DISCUSSION

Before modifying negative thoughts, enhancement of self-awareness ability can help improve negative symptoms and thereby improve the performance of social functions. Future research should develop a hierarchical program of negative symptoms, from cognition rehabilitation to enhancement of self-awareness, and end with modifying maladaptive beliefs.

摘要

目的

本研究提出并评估了一个理论模型,以探讨慢性精神分裂症个体的神经认知、自我挫败信念、体验性阴性症状和社会功能之间的关系。

方法

该研究招募了 229 名来自门诊和精神卫生医院日间病房的精神分裂症和分裂情感障碍患者。在获得知情同意后,参与者接受了回溯数字广度、数字符号测试以及自我挫败信念、体验性阴性症状和社会功能的测量。采用结构方程模型评估假设模型的拟合度,使用拟合指数、比较拟合指数、近似均方根误差和标准化均方根残差等指标进行模型评估。

结果

假设模型具有较好的拟合度。研究结果表明,神经认知可能通过对体验性阴性症状的影响间接影响自我挫败信念。与预期相反,研究并未观察到神经认知、自我挫败信念或阴性症状对社会功能的直接影响。修正后的模型揭示了体验性阴性症状在中介神经认知和社会功能之间关系中的作用。然而,自我挫败信念对社会功能没有显著影响。

讨论

在修正消极思维之前,增强自我意识能力有助于改善阴性症状,从而提高社会功能表现。未来的研究应制定一个从认知康复到增强自我意识再到修正不良信念的层级性阴性症状方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01ab/11323583/d12180b49ead/12888_2024_6003_Fig1_HTML.jpg

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