Rac Goran, James Christopher, Ellis Jeffrey L, Barton Gregory J, Blackwell Robert H, Gupta Gopal N
Department of Urology, Loyola University Medical Center, Maywood, Illinois, USA.
Department of Urology, Southern Illinois University, Springfield, Illinois, USA.
J Surg Oncol. 2024 Oct;130(5):1097-1103. doi: 10.1002/jso.27810. Epub 2024 Aug 13.
In surgically excising renal masses, studies have demonstrated that tumor enucleation is an effective option. However, there is limited literature comparing off-clamp to on-clamp tumor enucleation.
We retrospectively reviewed the charts of 189 patients who underwent robotic-assisted laparoscopic partial nephrectomy via tumor enucleation by a single surgeon from March 2012 and April 2022. Patients were stratified based on use of renal hilar clamping intraoperatively. Surgical, oncologic, and renal functional outcomes were captured. Variables were analyzed and compared between the two groups using Student's T-tests and Chi-square tests.
Of 189 procedures analyzed, 124 were performed on-clamp and 65 were performed off-clamp. There were no differences in patient demographics or average length of follow-up. There were no differences in estimated blood loss, complications, or hospital length of stay. Recurrence rates were similar for the two groups. The absolute difference in estimated glomerular filtration rate change between the two groups at time of first follow-up was not significant (p = 0.25).
There is no significant difference in perioperative outcomes such as surgical time, blood loss, or complications between the two groups. Furthermore, there was no significant difference in postoperative kidney function between the two techniques.
在手术切除肾肿物方面,研究表明肿瘤剜除术是一种有效的选择。然而,比较非阻断性与阻断性肿瘤剜除术的文献有限。
我们回顾性分析了2012年3月至2022年4月间由同一位外科医生通过肿瘤剜除术实施机器人辅助腹腔镜肾部分切除术的189例患者的病历。根据术中是否使用肾门阻断对患者进行分层。记录手术、肿瘤学及肾功能相关结局。使用学生t检验和卡方检验对两组间的变量进行分析和比较。
在分析的189例手术中,124例为阻断性手术,65例为非阻断性手术。患者人口统计学特征及平均随访时间无差异。估计失血量、并发症及住院时间无差异。两组的复发率相似。首次随访时两组间估计肾小球滤过率变化的绝对差异无统计学意义(p = 0.25)。
两组间围手术期结局如手术时间、失血量或并发症方面无显著差异。此外,两种技术在术后肾功能方面也无显著差异。