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通过目标导向性阶段训练改善脑外伤术后患者的纤维蛋白原、血管生成素-1、血管内皮生长因子、脑源性神经营养因子水平。

The improvement of fibrinogen, Ang-1, VEGF, BDNF in post-operative patients with brain trauma through target task-oriented phase training.

作者信息

Liu Bo, Yu Huan

机构信息

The First Affiliated Hospital of Harbin Medical University, Neurosurgery Department, Harbin, China.

The 242nd Hospital Harbin, Rehabilitation Medicine Department, Harbin, China.

出版信息

J Med Biochem. 2024 Jun 15;43(4):378-386. doi: 10.5937/jomb0-45490.

DOI:10.5937/jomb0-45490
PMID:39139152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11318060/
Abstract

BACKGROUND

It aims to explore the effect of target task-oriented phase training on fibrinogen (Fbg), angiopoietin (Ang-1), vascular endothelial growth factor (VEGF), serum brain-derived neurotrophic factor (BDNF), and quality of life in post-operative patients with brain trauma.

METHODS

142 patients with brain trauma who were operated on in neurosurgery of our hospital from March 2020 to March 2023 were chosen and separated into two groups by random number table. The control group (n=71) received routine post-operative training. The experimental group (n=71) received target task-oriented training based on the control group, and the serum cell levels of nursing for 3, 7, and 14 days were compared. Improvement of limb function and quality of life after 2, 4, and 6 weeks of nursing care is observed.

摘要

背景

旨在探讨目标任务导向阶段性训练对脑外伤术后患者纤维蛋白原（Fbg）、血管生成素（Ang-1）、血管内皮生长因子（VEGF）、血清脑源性神经营养因子（BDNF）及生活质量的影响。

方法

选取2020年3月至2023年3月在我院神经外科接受手术治疗的142例脑外伤患者，采用随机数字表法分为两组。对照组（n = 71）接受术后常规训练。实验组（n = 71）在对照组基础上接受目标任务导向训练，比较护理3天、7天和14天时的血清细胞水平。观察护理2周、4周和6周后肢体功能及生活质量的改善情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/11318060/338abb2523a8/jomb-43-3-2403378L_g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/11318060/aadb7cd1bdd4/jomb-43-3-2403378L_g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/11318060/4edd41e4ba95/jomb-43-3-2403378L_g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/11318060/338abb2523a8/jomb-43-3-2403378L_g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/11318060/aadb7cd1bdd4/jomb-43-3-2403378L_g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/11318060/4edd41e4ba95/jomb-43-3-2403378L_g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/11318060/338abb2523a8/jomb-43-3-2403378L_g003.jpg

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本文引用的文献

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Impact of fibrinogen level on the prognosis of patients with traumatic brain injury: a single-center analysis of 2570 patients.纤维蛋白原水平对创伤性脑损伤患者预后的影响：一项 2570 例患者的单中心分析。
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Effects of physical therapy interventions on balance ability in people with traumatic brain injury: A systematic review.物理治疗干预对创伤性脑损伤患者平衡能力的影响：一项系统综述。
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