Zawadzki Radosław, Rogalska Weronika, Pałdyna Marianna, Głuszczuk Dominika, Zajkowska Joanna, Kubas Bożena
Department of Radiology, Medical University of Białystok, Białystok, Poland.
Department of Infectious Diseases and Neuroinfections, Medical University of Białystok, Białystok, Poland.
Pol J Radiol. 2024 Jul 19;89:e345-e357. doi: 10.5114/pjr/189214. eCollection 2024.
Listeriosis caused by due to its ability to withstand harsh conditions and form biofilms on post-processed food poses a serious public health issue. It typically manifests itself with fever and gastrointestinal symptoms, but it can escalate with life-threatening conditions, especially in immunocompromised patients, the elderly, oncologically sick, and even pregnant women. The diagnosis is based on blood and cerebrospinal fluid culture growth, but it presents significant challenges due to deceptive findings and low positivity rates, the golden standard includes molecular diagnostic tests such as real-time PCR and metagenomic next-generation sequencing, which offer higher sensitivity and rapid detection. Radiological imaging, particularly magnetic resonance imaging, can play a crucial role in diagnosis of central nervous system (CNS) invasion by , enabling the detection of characteristic CNS lesions. The aim of the paper was to sum up the imaging features of CNS invasions in conventional imaging techniques, which can potentially speed up the diagnostic workflow for patients presenting with neurological symptoms associated with infection, particularly when conventional tests yield inconclusive results.
由[病原体名称未给出]引起的李斯特菌病，因其能够耐受恶劣条件并在加工后的食品上形成生物膜，构成了严重的公共卫生问题。它通常表现为发热和胃肠道症状，但可能会发展为危及生命的状况，尤其是在免疫功能低下的患者、老年人、肿瘤患者甚至孕妇中。诊断基于血液和脑脊液培养结果，但由于存在误导性发现和阳性率低的问题，诊断面临重大挑战，金标准包括分子诊断测试，如实时聚合酶链反应（PCR）和宏基因组下一代测序，这些方法具有更高的灵敏度和快速检测能力。放射学成像，特别是磁共振成像，在诊断[病原体名称未给出]对中枢神经系统（CNS）的侵袭中可发挥关键作用，能够检测到特征性的中枢神经系统病变。本文的目的是总结传统成像技术中[病原体名称未给出]中枢神经系统侵袭的成像特征，这可能会加快对出现与[病原体名称未给出]感染相关神经症状患者的诊断流程，特别是当传统检测结果不明确时。
