Barbey S, Monnet J P, Nezelof C, Gane P, Nogues C
Pathol Res Pract. 1985 Dec;180(6):584-9. doi: 10.1016/S0344-0338(85)80036-4.
Expression of HLADR, I, i blood group antigen and T6 antigen were studied in Histiocytosis X cells and pulmonary alveolar macrophages using double labelling immunofluorescence technique or immuno-peroxidase procedure. Alveolar macrophages express simultaneously HLADR and i blood group antigen. Histiocytosis X cells, characterized by HLADR and T6 antigens, and by their ultra-structural marker do not express i antigen. These results confirm the hypothesis that histiocytosis X cells constitute a specialized sub-population of the mononuclear phagocyte system.
采用双标记免疫荧光技术或免疫过氧化物酶法，对组织细胞增多症X细胞和肺泡巨噬细胞中的HLADR、I、i血型抗原及T6抗原表达进行了研究。肺泡巨噬细胞同时表达HLADR和i血型抗原。以HLADR和T6抗原及其超微结构标记为特征的组织细胞增多症X细胞不表达i抗原。这些结果证实了组织细胞增多症X细胞构成单核吞噬细胞系统一个特殊亚群的假说。
