Cambazard F, Fernandez-Bussy R, Schmitt D, Thivolet J
Ann Dermatol Venereol. 1983;110(1):33-40.
Three clinically and histopathologically typical cases of histiocytosis X have been studied by indirect immunofluorescence using monoclonal antibodies on skin lesions. An ultrastructural and immunoperoxidase technique has also been performed. The results confirm that the proliferative skin population of histiocytosis X is composed of Langerhans cells and that histochemical immunology is an effective process which can replace electron microscopy to confirm the diagnosis.
利用单克隆抗体,通过间接免疫荧光法对3例临床和组织病理学典型的组织细胞增多症X患者的皮肤损害进行了研究。同时还采用了超微结构和免疫过氧化物酶技术。结果证实,组织细胞增多症X的增殖性皮肤细胞群由朗格汉斯细胞组成,并且组织化学免疫学是一种有效的方法,可替代电子显微镜来确诊。