Strauss David, Cho Eric, Loecher Matthew, Lee Matthew, Eun Daniel
Department of Urology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Asian J Urol. 2024 Jul;11(3):366-372. doi: 10.1016/j.ajur.2023.12.001. Epub 2024 Mar 29.
A vesicourethral anastomotic leak (VUAL) is a known complication following robotic-assisted radical prostatectomy. The natural history of a VUAL has been well described and is frequently managed with prolonged catheterization. With increasing emphasis on patient reported outcomes, catheter duration and VUAL are associated with significant short-term quality of life impairment. We aimed to present a case series of our robotic early post-prostatectomy anastomotic repair technique, defined as revision within 6 weeks from index surgery.
A single institution prospective database identified eleven patients with a VUAL from July 2016 to October 2022 who underwent robotic early post-prostatectomy anastomotic repair by a single surgeon. Patients were diagnosed with a VUAL on pre-operative CT urogram or CT/fluoroscopic cystogram. The primary outcome was resolution of the anastomotic leak, defined as no contrast extravasation on post-operative cystography. Secondary outcomes included post-repair catheter duration and continence on the last follow-up defined as pad(s) per day.
The mean time to intervention after robotic-assisted radical prostatectomy was 21 days. Eight of the eleven (72.7%) patients had no evidence of extravasation on post-repair cystogram. The range from intervention to first cystogram was 7-20 days. The median catheter duration for those with successful intervention was 10 days. The median catheter duration for those with the leak on initial post-operative cystogram was 20 days. At a mean follow-up time of 25 months, eight (72.7%) patients reported using no pads per day, and three (27.3%) patients reported one pad per day.
Management of a VUAL has traditionally relied on prolonged catheter drainage and the tincture of time. As the role of robotic reconstruction has been shown to be a viable modality for management of bladder neck contracture, it is important to reconsider prior dogmas of urologic care. Our case series suggests that an early repair is safe and has a high success rate. Early robotic intervention gives providers an additional tool in aiding patient recovery.
膀胱尿道吻合口漏(VUAL)是机器人辅助根治性前列腺切除术后已知的一种并发症。VUAL的自然病程已有详细描述,通常通过延长导尿时间来处理。随着对患者报告结局的日益重视,导尿时间和VUAL与显著的短期生活质量损害相关。我们旨在展示一系列采用机器人辅助前列腺切除术后早期吻合口修复技术的病例,该技术定义为在初次手术6周内进行的修复手术。
一个单机构前瞻性数据库确定了2016年7月至2022年10月期间11例发生VUAL且由同一外科医生进行机器人辅助前列腺切除术后早期吻合口修复的患者。患者在术前CT尿路造影或CT/荧光透视膀胱造影中被诊断为VUAL。主要结局是吻合口漏的解决,定义为术后膀胱造影无造影剂外渗。次要结局包括修复后导尿时间以及最后一次随访时的控尿情况,控尿情况定义为每天使用尿垫的数量。
机器人辅助根治性前列腺切除术后至干预的平均时间为21天。11例患者中有8例(72.7%)在修复后膀胱造影中无外渗证据。从干预到首次膀胱造影的时间范围为7 - 20天。干预成功患者的中位导尿时间为10天。术后初次膀胱造影时有漏的患者的中位导尿时间为20天。在平均25个月的随访时间里,8例(72.7%)患者报告每天不使用尿垫,3例(27.3%)患者报告每天使用1个尿垫。
VUAL的处理传统上依赖于延长导尿引流时间和时间的作用。由于机器人重建已被证明是治疗膀胱颈挛缩的一种可行方式,因此重新审视泌尿外科护理的既往教条很重要。我们的病例系列表明早期修复是安全的且成功率高。早期机器人干预为医护人员提供了帮助患者康复的额外工具。