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外阴巨大细胞性血管纤维瘤:一例报告

Massive cellular angiofibroma of the vulva: a case report.

作者信息

Mahfoud Hounaida, Bensrhir Ibtissam, Abbouch Meryem, Mustapha Eid Chourouq, Meziane Mariame, Sassi Samia, Lamalmi Najat, Zeraidi Najia, Baidada Aziz

机构信息

Gynaecology-Obstetrics and Endoscopy Department, Maternity Souissi, University Hospital Center IBN SINA, University Mohammed V, Rabat 10100, Morocco.

Department of Dermatology, University Hospital Center IBN SINA, University Mohammed V, Rabat 10100, Morocco.

出版信息

J Surg Case Rep. 2024 Aug 13;2024(8):rjae508. doi: 10.1093/jscr/rjae508. eCollection 2024 Aug.

Abstract

Cellular angiofibroma is a rare benign mesenchymal tumor, typically occurring in the vulvar region of middle-aged women. This report highlights the importance of histological analysis in diagnosing this uncommon condition and emphasizes its benign nature and straightforward management. We present a case of a 58-year-old North African woman who had a large, well-defined mass in the left labia majora, which had been evolving over 2 years. MRI confirmed the resectability of the tumor by delineating its boundaries. The tumor, despite its slow growth leading to delayed diagnosis, was effectively treated with wide surgical excision. Diagnosis was confirmed through histological and immunohistochemical evaluations, revealing spindle cell proliferation with thick-walled vessels. Cellular angiofibroma, although initially alarming due to its size, is generally managed successfully with surgery and prognosis is favorable with a low risk of recurrence.

摘要

细胞性血管纤维瘤是一种罕见的良性间叶组织肿瘤,通常发生于中年女性的外阴区域。本报告强调了组织学分析在诊断这种罕见病症中的重要性,并强调了其良性本质和简单的治疗方法。我们报告一例58岁的北非女性,其左侧大阴唇有一个边界清晰的大肿块,已存在2年。磁共振成像(MRI)通过描绘肿瘤边界证实了其可切除性。尽管肿瘤生长缓慢导致诊断延迟,但通过广泛手术切除得到了有效治疗。通过组织学和免疫组化评估确诊,显示有梭形细胞增生和厚壁血管。细胞性血管纤维瘤尽管最初因其大小令人担忧,但一般通过手术可成功治疗,复发风险低,预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccae/11321720/1d8f4d3515b6/rjae508f1.jpg

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