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模拟医疗补助扩大对北卡罗来纳州阿片类药物流行的影响。

Simulating the effects of medicaid expansion on the opioid epidemic in North Carolina.

作者信息

Berghammer Anthony, Adams Joella W, Khan Sazid, Bobashev Georgiy

机构信息

RTI International  Research Triangle Park, 3040 East Cornwallis Road P.O. Box 12194, NC 27709-2194, United States.

出版信息

Drug Alcohol Depend Rep. 2024 Jul 17;12:100262. doi: 10.1016/j.dadr.2024.100262. eCollection 2024 Sep.

DOI:10.1016/j.dadr.2024.100262
PMID:39139778
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11320412/
Abstract

Expanding Medicaid plays a large role in ensuring that people across the United States have access to health care services. Although North Carolina recently moved toward Medicaid expansion, the impact of expansion on overdoses and overdose mortality may vary based on the type of treatment (offering medications for opioid use disorder [MOUD] vs. offering inpatient medically managed withdrawal without linkage to further MOUD treatment or non-MOUD-based treatment) accessed by individuals newly eligible for treatment through expansion. Based on official North Carolina statistics and published peer-reviewed literature, we developed a simulation model that forecasts opioid overdose and mortality under different scenarios for type of treatment accessed (MOUD-based vs. non-MOUD-based) and Medicaid coverage levels. An optimistic scenario assuming 70 % of individuals newly eligible for treatment would enter treatment during the first year of expansion estimated that 332 (Simulation Interval: 246-412) overdose deaths would be averted. A scenario more in line with recent historical trends assuming 38 % of individuals newly eligible for treatment would enter treatment resulted in 213 (Simulation Interval: 157-263) averted overdose deaths. In all scenarios, MOUD-based treatment approaches increased the number of lives saved compared with approaches expanding opioid treatment through non-MOUD-based treatment. Our study emphasized the need to ensure access to MOUD-based treatment for individuals newly covered by the Medicaid expansion.

摘要

扩大医疗补助计划在确保美国各地民众能够获得医疗服务方面发挥着重要作用。尽管北卡罗来纳州最近朝着扩大医疗补助计划的方向迈进,但扩大计划对药物过量及药物过量死亡率的影响可能因新符合条件通过扩大计划接受治疗的个人所获得的治疗类型(提供阿片类药物使用障碍药物治疗[MOUD]与提供住院医疗管理的戒断治疗但不与进一步的MOUD治疗或非基于MOUD的治疗相联系)而有所不同。基于北卡罗来纳州的官方统计数据和已发表的同行评审文献,我们开发了一个模拟模型,该模型预测在不同的治疗类型(基于MOUD与非基于MOUD)和医疗补助覆盖水平的情况下阿片类药物过量及死亡率。一个乐观的情景假设70%新符合治疗条件的个人将在扩大计划的第一年进入治疗,估计可避免332例(模拟区间:246 - 412)药物过量死亡。一个更符合近期历史趋势的情景假设38%新符合治疗条件的个人将进入治疗,结果可避免213例(模拟区间:157 - 263)药物过量死亡。在所有情景中,与通过非基于MOUD的治疗扩大阿片类药物治疗的方法相比,基于MOUD的治疗方法挽救的生命数量更多。我们的研究强调了确保新纳入医疗补助扩大计划覆盖范围的个人能够获得基于MOUD的治疗的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/577e/11320412/f0857d4dfcf4/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/577e/11320412/969580cabf6c/gr1.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/577e/11320412/ef9605377e8b/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/577e/11320412/f0857d4dfcf4/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/577e/11320412/969580cabf6c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/577e/11320412/293babfeea3b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/577e/11320412/5188907e60f5/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/577e/11320412/ef9605377e8b/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/577e/11320412/f0857d4dfcf4/gr5.jpg

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本文引用的文献

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Drug Alcohol Depend. 2024 Mar 1;256:111125. doi: 10.1016/j.drugalcdep.2024.111125. Epub 2024 Feb 14.
2
Use of Medication for Opioid Use Disorder Among Adults With Past-Year Opioid Use Disorder in the US, 2021.2021年美国过去一年患有阿片类药物使用障碍的成年人中用于阿片类药物使用障碍的药物使用情况。
JAMA Netw Open. 2023 Aug 1;6(8):e2327488. doi: 10.1001/jamanetworkopen.2023.27488.
3
Has the treatment gap for opioid use disorder narrowed in the U.S.?: A yearly assessment from 2010 to 2019".
美国阿片类药物使用障碍的治疗差距是否缩小了?2010 年至 2019 年的年度评估。
Int J Drug Policy. 2022 Dec;110:103786. doi: 10.1016/j.drugpo.2022.103786. Epub 2022 Aug 4.
4
"You're Not Supposed to be on it Forever": Medications to Treat Opioid Use Disorder (MOUD) Related Stigma Among Drug Treatment Providers and People who Use Opioids.“你不应该永远依赖它”:治疗阿片类药物使用障碍(MOUD)的药物在药物治疗提供者和使用阿片类药物者中相关的污名化问题
Subst Abuse. 2022 Jun 27;16:11782218221103859. doi: 10.1177/11782218221103859. eCollection 2022.
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Population-level impact of initiating pharmacotherapy and linking to care people with opioid use disorder at inpatient medically managed withdrawal programs: an effectiveness and cost-effectiveness analysis.在住院医学管理戒断项目中,为阿片类使用障碍患者启动药物治疗和联系护理对人群的影响:一项有效性和成本效益分析。
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