Bandara Amnp, Subasinghe Duminda
University Surgical Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka.
Division of HPB Surgery, Department of Surgery, University of Colombo, Sri Lanka.
SAGE Open Med Case Rep. 2024 Aug 12;12:2050313X241271780. doi: 10.1177/2050313X241271780. eCollection 2024.
Melioidosis is caused by community-acquired gram-negative bacillus which resides in soil and water. It was first described in 1912 in Burma and 1927 in Sri Lanka. Melioidosis presents with non-specific clinical and biochemical findings. Diagnosis is confirmed by the isolation of bacteria in cultures or demonstrating antibody response. Once the diagnosis is made, patients are managed with a course of intravenous antibiotics followed by a long course of oral antibiotics. Even with antibiotic treatments, most patients do not achieve complete recovery which results in chronic disease. Prolonged antibiotic therapy makes patients less compliant with treatment. Here we present a 50-year-old Sri Lankan male with diabetes mellitus presented with low-grade fever and back pain. He was found to have multiple abscesses involving the liver, spleen and left psoas muscle. Initially, he was evaluated for tuberculosis and later only melioidosis was diagnosed. The patient was managed with guided aspiration of abscesses and intravenous antibiotics. Subsequently, the patient defaulted on all treatments. It is important to consider melioidosis as a differential diagnosis in immunocompromised patients presented with multiple abscesses. It is important to maintain a registry for follow-up melioidosis patients to prevent becoming chronic melioidosis patients and to save healthcare costs.
类鼻疽病由一种存在于土壤和水中的社区获得性革兰氏阴性杆菌引起。它于1912年在缅甸首次被描述,1927年在斯里兰卡被描述。类鼻疽病表现出非特异性的临床和生化特征。通过在培养物中分离细菌或证明抗体反应来确诊。一旦确诊,患者先接受一个疗程的静脉抗生素治疗,随后是一个长疗程的口服抗生素治疗。即使进行抗生素治疗,大多数患者也无法完全康复,从而导致慢性病。长期的抗生素治疗使患者对治疗的依从性降低。在此,我们报告一名50岁的斯里兰卡男性糖尿病患者,出现低热和背痛。他被发现有多个脓肿,累及肝脏、脾脏和左腰大肌。最初,他接受了结核病评估,后来仅被诊断为类鼻疽病。该患者接受了脓肿的引导穿刺抽吸和静脉抗生素治疗。随后,该患者放弃了所有治疗。对于出现多个脓肿的免疫功能低下患者,将类鼻疽病作为鉴别诊断很重要。为类鼻疽病患者建立随访登记册以防止其成为慢性类鼻疽病患者并节省医疗费用很重要。