Akgül Erdal Meltem, Nayır Büyükşahin Halime, Güzelkaş İsmail, Sunman Birce, Alboğa Didem, Emiralioğlu Nagehan, Yalçın Ebru, Doğru Deniz, Özçelik H Uğur, Kiper Nural
Department of Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Türkiye.
Turk Arch Pediatr. 2024 Jul 1;59(4):370-374. doi: 10.5152/TurkArchPediatr.2024.23158.
Coronavirus disease 2019 pandemic caused many changes in the social behaviors of individuals and the provision of health systems. Many studies revealed reductions in the number of diagnoses and delays in diagnosis time during the pandemic. This study aimed to evaluate the effect of the pandemic on the time to diagnosis of major diseases of pediatric pulmonology. Newly diagnosed patients with cystic fibrosis (CF), childhood interstitial lung disease (chILD), tuberculosis (TB), and primary ciliary dyskinesia (PCD) were grouped into pandemic (group 1) and 2 consecutive pre-pandemic periods divided into equal intervals (groups 2 and 3). For each disease group, the time to diagnosis was compared between the specified periods. A total number of patients were 171 in this study. In the CF group, there was no statistically difference in time to diagnosis between periods. In the chILD group, there was a statistically significant difference in time to diagnosis (P = .036) between groups (group 1: 2 months, group 2: 4 months and group 3: 10.5 months) that was not originated from pandemic period. In TB group there was no statistically significant difference between groups. In the PCD group, the impact of the pandemic on the time to diagnosis could not be clarified because the time interval to diagnosis (minimum: 2 years, maximum: 16 years) exceeded the studied periods (21 months). In our study, no effect found between the pandemic and age at diagnosis or time to diagnosis in patients with PCD, chILD, CF, and TB at our center.
2019年冠状病毒病大流行给个人的社会行为和卫生系统的提供带来了许多变化。许多研究表明，大流行期间诊断数量减少，诊断时间延迟。本研究旨在评估大流行对小儿肺病主要疾病诊断时间的影响。新诊断的囊性纤维化（CF）、儿童间质性肺病（chILD）、结核病（TB）和原发性纤毛运动障碍（PCD）患者被分为大流行组（第1组）和连续两个大流行前时期，且这两个时期被等分为两个时间段（第2组和第3组）。对于每个疾病组，比较特定时间段之间的诊断时间。本研究共有171例患者。在CF组中，各时间段之间的诊断时间无统计学差异。在chILD组中，各时间段之间的诊断时间存在统计学显著差异（P = 0.036）（第1组：2个月，第2组：4个月，第3组：10.5个月），且差异并非源于大流行时期。在TB组中，各时间段之间无统计学显著差异。在PCD组中，由于诊断时间间隔（最短：2年，最长：16年）超过了研究时间段（21个月），因此无法明确大流行对诊断时间的影响。在我们的研究中，在我们中心，大流行与PCD、chILD、CF和TB患者的诊断年龄或诊断时间之间未发现影响。
