Zhang Yulong, Hu Bowen, Chen Yushuang, Wang Zhen
Chongqing Key Laboratory of Green Synthesis and Application, College of Chemistry, Chongqing Normal University, Chongqing, 401331, People's Republic of China.
College of Chemistry and Chemical Engineering, Chongqing University of Science and Technology, Chongqing, 401331, People's Republic of China.
Chemistry. 2024 Oct 23;30(59):e202402469. doi: 10.1002/chem.202402469. Epub 2024 Oct 4.
The past few decades have witnessed tremendous development within epoxides. Among the many known reactions involving epoxide, Meinwald rearrangements represent one of the most important and attractive approaches, which can transform epoxides into versatile carbonyl compounds. Given the high efficiency of this protocol, substantial efforts have been made by researchers by utilizing multiple catalyst systems. This review provides an overview of recent advances in the Meinwald rearrangement (from 2014 onward), along with detailed discussions on mechanistic insights. This review aims to highlight the importance and value of these methodologies, thereby promoting further investigation and application.
在过去几十年里，环氧化合物领域取得了巨大的发展。在众多已知的涉及环氧化合物的反应中，迈因瓦尔德重排是最重要且最具吸引力的方法之一，它能将环氧化合物转化为多种羰基化合物。鉴于该反应方案的高效性，研究人员利用多种催化剂体系做出了大量努力。本综述概述了迈因瓦尔德重排（自2014年起）的最新进展，并对其机理进行了详细讨论。本综述旨在突出这些方法的重要性和价值，从而推动进一步的研究和应用。
