Private Dental Surgeon, Chennai, Tamil Nadu, India.
Center for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Tamil Nadu, India.
Neurosurg Rev. 2024 Aug 14;47(1):430. doi: 10.1007/s10143-024-02694-5.
This letter commends the article by Luzzi et al. on alternative neuroprotection strategies for aneurysmal subarachnoid hemorrhage (SAH). It highlights the pharmacological advantages of nicardipine, cilostazol, and clazosentan over nimodipine in managing cerebral vasospasm and delayed cerebral ischemia. Emphasizing the need for personalized medicine, it advocates for integrating genetic screening and advanced monitoring techniques to tailor treatments to individual patient profiles. This approach could significantly improve clinical outcomes by optimizing drug efficacy and minimizing adverse effects.
这封信赞扬了 Luzzi 等人关于颅内动脉瘤性蛛网膜下腔出血(SAH)的替代神经保护策略的文章。它强调了尼卡地平、西洛他唑和克拉生坦在治疗脑血管痉挛和迟发性脑缺血方面相对于尼莫地平的药理学优势。该文强调了个性化医疗的必要性,主张整合基因筛查和先进的监测技术,根据个体患者的特点定制治疗方案。这种方法可以通过优化药物疗效和最小化不良反应,显著改善临床结果。