体外胰岛素对正常和糖尿病大鼠红细胞膜乙酰胆碱酯酶的作用。
In vitro insulin effect on acetylcholine esterase of erythrocyte membranes of normal and diabetic rats.
作者信息
Agarwal V R, Rastogi A K, Sahib M K, Sagar P
出版信息
Acta Diabetol Lat. 1985 Oct-Dec;22(4):359-63. doi: 10.1007/BF02624755.
PMID:3914160
Abstract
Alloxan induced diabetes in rats was associated with a significant reduction in the acetylcholine esterase activity of the erythrocyte membrane. Preincubation of these membranes with insulin caused a rapid but transient stimulation of this enzyme activity in both normal and diabetic rats, the effect being more marked in the latter group.
摘要
四氧嘧啶诱导的大鼠糖尿病与红细胞膜乙酰胆碱酯酶活性显著降低有关。用胰岛素对这些膜进行预孵育，在正常大鼠和糖尿病大鼠中均引起该酶活性的快速但短暂的刺激，在后一组中这种作用更为明显。
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