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体外胰岛素对正常和糖尿病大鼠红细胞膜乙酰胆碱酯酶的作用。

In vitro insulin effect on acetylcholine esterase of erythrocyte membranes of normal and diabetic rats.

作者信息

Agarwal V R, Rastogi A K, Sahib M K, Sagar P

出版信息

Acta Diabetol Lat. 1985 Oct-Dec;22(4):359-63. doi: 10.1007/BF02624755.

DOI:10.1007/BF02624755
PMID:3914160
Abstract

Alloxan induced diabetes in rats was associated with a significant reduction in the acetylcholine esterase activity of the erythrocyte membrane. Preincubation of these membranes with insulin caused a rapid but transient stimulation of this enzyme activity in both normal and diabetic rats, the effect being more marked in the latter group.

摘要

四氧嘧啶诱导的大鼠糖尿病与红细胞膜乙酰胆碱酯酶活性显著降低有关。用胰岛素对这些膜进行预孵育，在正常大鼠和糖尿病大鼠中均引起该酶活性的快速但短暂的刺激，在后一组中这种作用更为明显。

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In vitro insulin effect on acetylcholine esterase of erythrocyte membranes of normal and diabetic rats.体外胰岛素对正常和糖尿病大鼠红细胞膜乙酰胆碱酯酶的作用。
Acta Diabetol Lat. 1985 Oct-Dec;22(4):359-63. doi: 10.1007/BF02624755.
2
Biomembrane cooperative enzymes. In vivo modulation of rat erythrocyte acetylcholinesterase by insulin in normal and diabetic conditions.
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4
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Erythrocyte membrane acetylcholinesterase in type 1 (insulin-dependent) diabetes mellitus.1型（胰岛素依赖型）糖尿病患者红细胞膜乙酰胆碱酯酶
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引用本文的文献

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Insulin or sulfonylurea treatments of the diabetics differentially affect erythrocyte membrane and serum enzymes and extent of protein glycosylation.糖尿病患者接受胰岛素或磺脲类药物治疗对红细胞膜、血清酶及蛋白质糖基化程度有不同影响。
Indian J Clin Biochem. 2001 Jan;16(1):81-8. doi: 10.1007/BF02867573.
2
In vitro insulin action on erythrocyte glucose metabolism in normal and diabetic rats.
Diabetologia. 1988 Jan;31(1):51-3. doi: 10.1007/BF00279133.
3
Erythrocyte membrane acetylcholinesterase in type 1 (insulin-dependent) diabetes mellitus.1型（胰岛素依赖型）糖尿病患者红细胞膜乙酰胆碱酯酶

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes.人红细胞无血红蛋白空泡的制备及其化学特性
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A new and rapid colorimetric determination of acetylcholinesterase activity.一种新的快速比色法测定乙酰胆碱酯酶活性。
Biochem J. 1989 May 1;259(3):897-9. doi: 10.1042/bj2590897.
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Effect of insulin on acetylcholinesterase activity.胰岛素对乙酰胆碱酯酶活性的影响。
Biochem Biophys Res Commun. 1981 Aug 31;101(4):1216-20. doi: 10.1016/0006-291x(81)91577-1.
5
The endocytotic-internalization pathway of insulin metabolism: relationship to insulin degradation and activation of glucose transport.胰岛素代谢的内吞内化途径：与胰岛素降解及葡萄糖转运激活的关系
Endocrinology. 1980 Dec;107(6):1937-45. doi: 10.1210/endo-107-6-1937.
6
The interaction of insulin with its receptor: cross-linking via insulin association as the source of receptor clustering.胰岛素与其受体的相互作用：通过胰岛素缔合进行交联作为受体聚集的来源。
Diabetologia. 1982 Nov;23(5):381-5, 391-2. doi: 10.1007/BF00260946.
7
Evidence for the presence of non-lipoprotein factors in diabetic serum capable of stimulating rat hepatic cholesterol-7 alpha-hydroxylase in vitro.有证据表明糖尿病血清中存在非脂蛋白因子，这些因子在体外能够刺激大鼠肝脏胆固醇7α-羟化酶。
Biochem Biophys Res Commun. 1984 Jun 29;121(3):743-8. doi: 10.1016/0006-291x(84)90741-1.
8
Effect of diabetes mellitus on two membrane integrated enzymes of erythrocytes of different ages.糖尿病对不同年龄红细胞的两种膜整合酶的影响。
Indian J Exp Biol. 1980 Jun;18(6):620-2.
9
Distribution of insulin receptors in human erythrocyte membranes. Insulin binding to sealed right-side-out and inside-out human erythrocyte vesicles.胰岛素受体在人红细胞膜中的分布。胰岛素与密封的外翻和内翻人红细胞囊泡的结合。
Biochim Biophys Acta. 1984 Aug 22;775(2):260-4. doi: 10.1016/0005-2736(84)90178-0.
10
Insulin receptors on erythrocytes and hepatocytes from streptozotocin induced diabetic rats.
Endocrinol Jpn. 1982 Oct;29(5):623-30. doi: 10.1507/endocrj1954.29.623.