Vanderbilt University, 111 21(st) Avenue South, Nashville, TN 37203, USA.
Joan & Sanford I. Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10065, USA.
J Affect Disord. 2024 Dec 1;366:74-82. doi: 10.1016/j.jad.2024.08.054. Epub 2024 Aug 12.
Repetitive negative thinking (RNT) is a transdiagnostic process involving perseverative, unproductive, and uncontrollable thoughts. Although RNT may impede adaptive psychosocial functioning by prolonging negative mood states, strengthening cognitive biases, and preventing effective problem-solving, the extent to which RNT is associated with risk for poor psychosocial outcomes is unclear. Given that this has clear transdiagnostic treatment implications, the present study aimed to isolate the unique relationship of RNT with social functioning and life satisfaction in a mixed clinical and non-clinical sample.
In 201 mid-to-later life adult participants (27 with primary diagnoses of bipolar disorder, 84 with major depressive disorder, and 90 healthy volunteers), we measured RNT, social functioning, life satisfaction, trait rumination, DSM-5 diagnoses, depressive symptoms, manic symptoms, cognitive control performance, and global cognitive functioning.
Linear regression models revealed that RNT, but not rumination, was significantly associated with poorer social functioning (β = 0.42 p < .001) and reduced life satisfaction (β = -0.42, p < .001) after controlling for clinical and cognitive covariates.
Limited demographic diversity, cross-sectional design, self-reporting of outcomes.
Results suggest that RNT may confer risk for key psychosocial outcomes during middle to later adulthood, over and above the effects of clinical and cognitive variables and independent of diagnostic status. Findings lend support to the notion of RNT as a transdiagnostic process and suggest that RNT may be an important therapeutic target for adults with poor social functioning and/or reduced life satisfaction.
重复性消极思维（RNT）是一种涉及持续、低效和无法控制的思维的跨诊断过程。虽然 RNT 可能通过延长负面情绪状态、强化认知偏差和防止有效解决问题来阻碍适应性的心理社会功能，但 RNT 与不良心理社会结果风险的关联程度尚不清楚。鉴于这具有明确的跨诊断治疗意义，本研究旨在在混合临床和非临床样本中孤立 RNT 与社交功能和生活满意度的独特关系。
在 201 名中年后期成年参与者（27 名原发性双相情感障碍、84 名重度抑郁症和 90 名健康志愿者）中，我们测量了 RNT、社交功能、生活满意度、特质性沉思、DSM-5 诊断、抑郁症状、躁狂症状、认知控制表现和总体认知功能。
线性回归模型显示，在控制临床和认知协变量后，RNT 而不是沉思与较差的社交功能（β=0.42，p<0.001）和降低的生活满意度（β= -0.42，p<0.001）显著相关。
样本的人口统计学多样性有限、横断面设计、结果的自我报告。
结果表明，RNT 可能在中年后期对关键心理社会结果产生风险，超过了临床和认知变量的影响，且独立于诊断状态。研究结果支持 RNT 作为一种跨诊断过程的概念，并表明 RNT 可能是社交功能差和/或生活满意度降低的成年人的重要治疗靶点。
