Department of Otolaryngology Surgery, The Second People's Hospital of Gansu Province (Affiliated Hospital of Northwest University for Nationalities), China.
J Int Med Res. 2024 Aug;52(8):3000605241259764. doi: 10.1177/03000605241259764.
Nodular fasciitis (NF) is a benign and self-limiting fibroblastic proliferation that originates from the superficial fascia and extends into the subcutaneous tissue or muscle. It typically manifests in individuals aged 20 to 35 years, with rare occurrences observed in patients over the age of 60 years. We herein report a case involving a 75-year-old man with NF in the right vocal cord. The patient sought medical attention at the Department of Otolaryngology of our hospital because of a 1-month history of hoarseness and breathlessness. The diagnosis was unable to be confirmed through preoperative pathological examination. After admission to our hospital, various examinations were completed and surgical treatment was performed, and the postoperative histopathological findings revealed the presence of NF in the right vocal cord. NF of the vocal cord is a rare clinical entity. Given its rapid progression and propensity for marked infiltration, it often poses diagnostic challenges because it can mimic various malignant soft tissue tumors. Therefore, thorough exclusion of other neoplastic lesions is imperative prior to confirming the diagnosis of NF through pathological examination. Local surgical resection remains the primary treatment modality.
结节性筋膜炎（NF）是一种良性、自限性的成纤维细胞增生性病变，起源于浅筋膜，可延伸至皮下组织或肌肉。它通常发生在 20 至 35 岁的个体中，60 岁以上的患者罕见。本文报告了一例发生于右侧声带的 75 岁男性 NF 病例。因声嘶和呼吸困难 1 个月，患者到我院耳鼻喉科就诊。术前病理检查未能明确诊断。入院后，完成了各种检查并进行了手术治疗，术后组织病理学检查结果显示右侧声带存在 NF。声带 NF 是一种罕见的临床实体。由于其快速进展和明显浸润的倾向，它常常给诊断带来挑战，因为它可以模拟各种恶性软组织肿瘤。因此，在通过病理检查明确 NF 诊断之前，必须彻底排除其他肿瘤性病变。局部手术切除仍然是主要的治疗方法。
