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原发性干燥综合征表现为低钾性周期性瘫痪和急性胰腺炎。

Primary Sjogren's syndrome presenting as hypokalaemic periodic paralysis and acute pancreatitis.

机构信息

General Medicine, All India Institute of Medical Sciences, Rishikesh, India.

General Medicine, All India Institute of Medical Sciences, Rishikesh, India

出版信息

BMJ Case Rep. 2024 Aug 14;17(8):e260646. doi: 10.1136/bcr-2024-260646.

Abstract

Renal tubular acidosis is a well-known consequence of primary Sjogren's syndrome (pSS), but a rare manifestation similar to acute pancreatitis in pSS. Here, we discuss the case of a woman in her 50s, who presented to a tertiary care hospital with recurrent episodes of sudden-onset weakness in all four limbs, recurrent vomiting and epigastric pain. She had non-anion gap metabolic acidosis with hypokalaemia and was diagnosed with pSS with hypokalaemic periodic paralysis. She was also diagnosed with acute pancreatitis based on elevated amylase and lipase levels and CT findings. The article highlights the diverse spectrum of clinical manifestations of pSS, including renal and pancreatic involvements, which can be rare consequences of the disease.

摘要

肾小管性酸中毒是原发性干燥综合征(pSS)的已知后果,但在 pSS 中也有类似急性胰腺炎的罕见表现。在这里,我们讨论了一位 50 多岁女性的病例,她因四肢突然无力反复发作、反复呕吐和上腹痛到三级保健医院就诊。她患有非阴离子间隙性代谢性酸中毒伴低钾血症,并被诊断为低钾性周期性麻痹 pSS。根据淀粉酶和脂肪酶水平升高以及 CT 结果,她还被诊断为急性胰腺炎。本文强调了 pSS 的临床表现的多样性,包括肾脏和胰腺受累,这可能是该疾病的罕见后果。

相似文献

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Hypokalemic paralysis revealing Sjögren's syndrome.低钾性麻痹揭示干燥综合征。
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Hypokalaemic periodic paralysis revealing primary Sjogren's syndrome.低钾性周期性麻痹揭示原发性干燥综合征
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