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干燥综合征继发远端肾小管酸中毒所致的低钾性麻痹。

Hypokalaemic paralysis precipitated by distal renal tubular acidosis secondary to Sjögren's syndrome.

作者信息

Comer D M, Droogan A G, Young I S, Maxwell A P

机构信息

Craigavon Area Hospital Group Trust, Craigavon BT63 5QQ, Northern Ireland.

出版信息

Ann Clin Biochem. 2008 Mar;45(Pt 2):221-5. doi: 10.1258/acb.2007.006080.

DOI:10.1258/acb.2007.006080
PMID:18325192
Abstract

A 43-year-old woman presented with a sudden onset of hypokalaemic paralysis requiring intubation and ventilatory support. Subsequent biochemical and clinical assessments established a diagnosis of distal renal tubular acidosis (RTA) in association with underlying Sjögren's syndrome as the aetiology of her profound hypokalaemia. Distal RTA is rare, but Sjögren's syndrome is one of the more common causes in adults and should be considered in the differential diagnosis of patients who present with hypokalaemic muscular paralysis.

摘要

一名43岁女性突发低钾性麻痹,需要插管和通气支持。随后的生化和临床评估确诊为远端肾小管酸中毒(RTA),并伴有潜在的干燥综合征,这是其严重低钾血症的病因。远端RTA较为罕见,但干燥综合征是成人中较常见的病因之一,对于出现低钾性肌肉麻痹的患者进行鉴别诊断时应予以考虑。

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Ann Clin Biochem. 2008 Mar;45(Pt 2):221-5. doi: 10.1258/acb.2007.006080.
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