Division of Microbiology, Department of Pathology and Laboratory Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Anatomical Pathology Department, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
J Med Case Rep. 2024 Aug 15;18(1):380. doi: 10.1186/s13256-024-04718-6.
Mycoplasma hominis is typically found on the mucosal epithelium of the human genital tract, with infections being rare. However, when the mucosal barrier is compromised or in individuals with weakened immune systems, this microorganism can trigger infections in both intragenital and extragenital sites. This study offers a comprehensive overview of infections caused by the rare pathogen M. hominis. This overview helps laboratories identify M. hominis infections in a timely manner, thereby enabling earlier clinical intervention for patients.
A 75-year-old Taiwanese man with type 2 diabetes mellitus initially underwent a left lower extremity amputation following a severe infection caused by necrotizing fasciitis. Subsequently, a poorly healing wound developed at the site of amputation. Upon culturing the wound abscess, M. hominis was isolated and identified as the causative agent.
Through this case, we present clinical and microbiological observations along with a review of the literature to deepen our understanding of M. hominis. Our findings can be used to develop laboratory diagnostic protocols and innovative therapeutic approaches.
人型支原体通常存在于人体生殖道的黏膜上皮，感染较为罕见。然而，当黏膜屏障受损或免疫系统较弱的个体，这种微生物可能会引发生殖道内和生殖道外部位的感染。本研究全面概述了由罕见病原体人型支原体引起的感染。这一概述有助于实验室及时识别人型支原体感染，从而为患者提供更早的临床干预。
一名 75 岁的台湾男性，患有 2 型糖尿病，最初因坏死性筋膜炎引起的严重感染而接受了左下肢截肢，随后截肢部位出现愈合不良的伤口。在对伤口脓肿进行培养时，分离出人型支原体并鉴定为病原体。
通过本病例，我们结合文献复习，介绍了临床和微生物学观察结果，加深了对人型支原体的认识。我们的发现可用于制定实验室诊断方案和创新治疗方法。
