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不同中医运动疗法对稳定期慢性阻塞性肺疾病患者肺功能的影响:网状 Meta 分析。

Effects of different traditional Chinese exercises on pulmonary function in patients with stable chronic obstructive pulmonary disease: a network meta-analysis.

机构信息

Key Laboratory of Sports Engineering of General Administration of Sports of China, Research Center of Sports Equipment Engineering Technology of Hubei Province, Wuhan Sports University, Wuhan, 430079, People's Republic of China.

Department of Rehabilitation Medicine, Beijing Jishuitan Hospital Guizhou Hospital, Guiyang, 550014, People's Republic of China.

出版信息

BMC Complement Med Ther. 2024 Aug 14;24(1):304. doi: 10.1186/s12906-024-04609-9.

Abstract

OBJECTIVE

Traditional Chinese exercises (Taichi, Wuqinxi, Liuzijue, and Baduanjin) are considered effective alternative treatments for improving symptoms in the stable phase of COPD. However, the most effective exercise remains unknown. This study compared the effectiveness of different traditional Chinese exercises on pulmonary function in patients with stable chronic obstructive pulmonary disease (COPD) using a network meta-analysis.

METHODS

From database establishment until September 2023, eligible randomized controlled trials (RCTs) were searched. Two reviewers performed the risk of bias assessment of the included studies using the Cochrane Collaboration tool, and the evidence level was suggested using the GRADE system.

RESULTS

Fifty-seven studies comprising 4294 patients were included. The results of the network meta-analysis show that Baduanjin was most effective in improving the forced expiratory volume in the first second (FEV1). However, Liuzijue significantly improved the first-second forced vital capacity percentage of expected value (FEV1%) and the ratio of the forced expiratory volume in the first second to the forced vital capacity (FEV1/FVC). The probability ranking results indicated that Liuzijue was the most effective, followed by Baduanjin, Wuqinxi, and Taichi. Subgroup analysis in conjunction with intervention duration revealed that Liuzijue had a significant advantage over other interventions for improving FEV1, FEV1%, and FEV1/FVC within 6 months and improved FEV1% and FEV1/FVC for ≥ 6 months. Moreover, Subgroup analysis based on baseline pulmonary function revealed that Liuzijue had a significant advantage over other interventions for improving FEV1% within severe and moderate groups. Finally, Subgroup analysis based on the frequency of interventions showed that Liuzijue was still more effective in improving FEV1, FEV1%, and FEV1/FVC in the ≥ three times one week.

CONCLUSION

Liuzijue was more effective than Taichi, Wuqinxi, Liuzijue, and Baduanjin in improving pulmonary function in patients with stable COPD.

摘要

目的

传统中医运动(太极拳、五禽戏、六字诀、八段锦)被认为是改善慢性阻塞性肺疾病稳定期症状的有效替代疗法。然而,最有效的运动方式仍不清楚。本研究通过网络荟萃分析比较了不同传统中医运动对稳定期慢性阻塞性肺疾病(COPD)患者肺功能的影响。

方法

从数据库建立到 2023 年 9 月,纳入了符合条件的随机对照试验(RCT)。两位评审员使用 Cochrane 协作工具评估纳入研究的偏倚风险,并使用 GRADE 系统建议证据水平。

结果

纳入了 57 项研究,共 4294 名患者。网络荟萃分析结果显示,八段锦在改善第一秒用力呼气量(FEV1)方面最有效。然而,六字诀显著改善了预计值的第一秒用力肺活量百分比(FEV1%)和第一秒用力呼气量与用力肺活量的比值(FEV1/FVC)。概率排序结果表明,六字诀最有效,其次是八段锦、五禽戏和太极拳。结合干预持续时间的亚组分析表明,六字诀在改善 6 个月内的 FEV1、FEV1%和 FEV1/FVC 方面优于其他干预措施,且改善 6 个月以上的 FEV1%和 FEV1/FVC。此外,基于基线肺功能的亚组分析表明,六字诀在严重和中度组中改善 FEV1%方面具有显著优势。最后,基于干预频率的亚组分析表明,六字诀在每周≥3 次的情况下,仍然更有效地改善 FEV1、FEV1%和 FEV1/FVC。

结论

六字诀比太极拳、五禽戏、八段锦更能有效改善稳定期 COPD 患者的肺功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81f8/11325568/d94db5eabe9a/12906_2024_4609_Fig1_HTML.jpg

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