Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Keelung Branch, Keelung.
Graduate Institute of Biomedical Informatics, Taipei Medical University.
Int J Surg. 2024 Aug 1;110(8):4581-4587. doi: 10.1097/JS9.0000000000001461.
The split-thickness skin graft (STSG) procedure is frequently used in the reconstruction of burn-injured patients. This study assessed the impact of graft timing on associated skin complications in patients with torso burns using a comprehensive national database.
Truncal burn (2nd-degree and 3rd-degree burns covering 20-89% TBSA) patients who underwent STSG in the National Trauma Data Bank from 2011 to 2015 were studied. The outcomes examined were graft-related complications (superficial surgical site infections, deep surgical site infections, and graft failure), overall mortality and hospital length of stay (LOS). Patients were compared based on the presence or absence of grafting complications. A linear regression model was used to assess the relationship between hospital LOS and graft timing, considering other variables.
Among the 853 studied patients, the cohort with graft complications exhibited a significantly prolonged time to STSG (413.0 h compared to 264.6 h, P<0.001) and a higher percentage of patients with pre-existing diabetes (18.5 vs. 8.0%, P=0.008). The multiple logistic regression analysis revealed that both the extended time to STSG (odds=1.001, P=0.003) and pre-existing diabetes (odds=2.790, P=0.010) significantly elevated the likelihood of complications associated with STSG. Notably, this delay did not elevate mortality risks. A positive relationship was found between grafting delay and LOS.
The findings underscore that a prolonged duration to skin grafting contributes to extended hospital stays and increased graft-related complications. However, the role of grafting delay in influencing the mortality of truncal burn patients appeared inconsequential, indicating that mortality may be influenced by various factors.
在烧伤患者的重建中,经常使用刃厚皮片移植(STSG)手术。本研究使用综合国家数据库评估供区时间对躯干烧伤患者相关皮肤并发症的影响。
研究对象为 2011 年至 2015 年国家创伤数据库中接受 STSG 的躯干烧伤(2 度和 3 度烧伤,烧伤面积占体表面积的 20-89%)患者。研究结果为移植相关并发症(浅表手术部位感染、深部手术部位感染和移植失败)、总死亡率和住院时间(LOS)。根据是否存在移植并发症对患者进行比较。使用线性回归模型评估 LOS 与移植时间之间的关系,并考虑其他变量。
在 853 名研究患者中,有移植并发症的队列 STSG 时间明显延长(413.0 小时与 264.6 小时,P<0.001),且更多患者患有预先存在的糖尿病(18.5%比 8.0%,P=0.008)。多变量逻辑回归分析显示,延长的 STSG 时间(优势比=1.001,P=0.003)和预先存在的糖尿病(优势比=2.790,P=0.010)均显著增加了与 STSG 相关的并发症的可能性。值得注意的是,这种延迟并未增加死亡率。发现移植延迟与 LOS 之间存在正相关关系。
研究结果表明,皮肤移植时间延长会导致住院时间延长和移植相关并发症增加。然而,移植延迟对躯干烧伤患者死亡率的影响似乎并不重要,这表明死亡率可能受到多种因素的影响。