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易损主动脉的筛查:针对人群中的高危群体

Screening for the vulnerable aorta: targeting high-risk groups in the population.

作者信息

Proietti Riccardo, Field Mark, McKay Victoria, Lip Gregory Y H, Kuduvalli Manoj

机构信息

Senior Clinical Lecturer.

Professor and Cardiac Surgeon.

出版信息

Br J Cardiol. 2023 Sep 5;30(3):25. doi: 10.5837/bjc.2023.025. eCollection 2023.

Abstract

Thoracic aortic aneurysms are often asymptomatic until patients present with a life-threatening acute aortic syndrome. The vulnerability of an aorta to an acute aortic syndrome is determined by cross-sectional diameter and underlying aetiological factors, such as genotype or acquired disease. Screening the general population for thoracic aneurysms presents multiple resource issues including the availability of imaging modalities. Targeted screening of high-risk groups provides the only currently pragmatic solution. Opportunistic imaging through lung cancer screening programmes could pick up a proportion. Until we have a comprehensive screening programme it is incumbent on all healthcare professionals to have a low threshold for considering acute aortic pathologies when reviewing patients presenting with chest pain.

摘要

胸主动脉瘤通常没有症状,直到患者出现危及生命的急性主动脉综合征。主动脉对急性主动脉综合征的易感性由横截面积和潜在病因决定,如基因型或后天性疾病。对普通人群进行胸主动脉瘤筛查存在多个资源问题,包括成像方式的可用性。对高危人群进行有针对性的筛查是目前唯一切实可行的解决方案。通过肺癌筛查计划进行机会性成像可以发现一部分病例。在我们有全面的筛查计划之前,所有医疗保健专业人员在评估胸痛患者时,都应保持较低的阈值来考虑急性主动脉病变。

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本文引用的文献

2
Inherited Thoracic Aortic Disease: New Insights and Translational Targets.遗传性胸主动脉疾病:新的见解和转化靶点。
Circulation. 2020 May 12;141(19):1570-1587. doi: 10.1161/CIRCULATIONAHA.119.043756. Epub 2020 May 11.

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