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正常受试者口服帕拉金糖后血糖和胰岛素的变化。

Changes in blood glucose and insulin after an oral palatinose administration in normal subjects.

作者信息

Kawai K, Okuda Y, Yamashita K

出版信息

Endocrinol Jpn. 1985 Dec;32(6):933-6. doi: 10.1507/endocrj1954.32.933.

DOI:10.1507/endocrj1954.32.933
PMID:3914416
Abstract

Changes in plasma glucose and insulin concentration in response to palatinose ingestion were compared with those to sucrose in eight normal volunteers. When 50 g of palatinose was administered, the plasma glucose gradually increased to its peak of 110.9 +/- 4.9 mg/dl at 60 min after administration and maintained a plateau during the 120 min of the experiment. The peak value of plasma glucose to 50 g sucrose in the same group was 143.3 +/- 8.8 mg/dl at 30 min after administration and then the value sharply decreased to the fasting level. The cumulative increase in plasma glucose (sigma delta PG) to palatinose was significantly smaller than that to sucrose. The changes in the plasma insulin level almost paralleled those in the plasma glucose level. These results indicate that palatinose is more slowly absorbed than sucrose and therefore useful as a sweetener for diabetic patients.

摘要

在八名正常志愿者中,比较了摄入帕拉金糖和蔗糖后血浆葡萄糖和胰岛素浓度的变化。给予50克帕拉金糖后,血浆葡萄糖在给药后60分钟逐渐升高至峰值110.9±4.9毫克/分升,并在实验的120分钟内保持平稳。同一组中,50克蔗糖给药后30分钟血浆葡萄糖峰值为143.3±8.8毫克/分升,然后该值急剧降至空腹水平。帕拉金糖导致的血浆葡萄糖累积增加量(∑ΔPG)明显小于蔗糖。血浆胰岛素水平的变化几乎与血浆葡萄糖水平的变化平行。这些结果表明,帕拉金糖的吸收比蔗糖慢,因此可作为糖尿病患者的甜味剂。

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