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西班牙胃肠道放射肿瘤学的现状:一项多中心真实世界调查及与关键临床指南的比较

Current landscape of gastrointestinal radiation oncology in Spain: a multicenter real-life survey and comparison with key clinical guidelines.

作者信息

Hernando-Requejo Ovidio, Olombrada Maria Victoria Torres, Bravo Irene Alda, Moreno Leire Arbea, López-Campos Fernando, Gonzalez Mercedes López, Martín Margarita Martín, Macías Virginia Morillo, De la Pinta Carolina

机构信息

Radiation Oncology Department, Sanchinarro University Hospital, Madrid, Spain.

Radiation Oncology Department, University Hospital Fuenlabrada, Madrid, Spain.

出版信息

Rep Pract Oncol Radiother. 2024 Jul 22;29(3):340-347. doi: 10.5603/rpor.101096. eCollection 2024.

DOI:10.5603/rpor.101096
PMID:39144273
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11321793/
Abstract

BACKGROUND

The GI Tumors Workgroup, a division of the Spanish Society of Radiation Therapy, conducted a survey in December 2020 to assess the adherence of radiation oncologists in Spain to international guidelines for gastrointestinal tumors.

MATERIALS AND METHODS

Using Google Forms, we designed a survey covering treatments for esophageal, gastric, pancreatic, and rectal cancers.

RESULTS

In esophageal cancer treatment, neoadjuvant chemoradiation was the standard in 76.7% of institutions. Radiation doses range from 41.1 to 50.4 Gy in conventional fractionation. Planning positron emission tomography-computed tomography (PET-CT) was performed in 83.3% of centers, and intensity-modulated radiation therapy/volumetric-arc radiation therapy (IMRT/VMAT) was the preferred technique in 86.7% of institutions. For gastric cancer, 71.4% followed perioperative chemotherapy guidelines. In the case of adjuvant radiotherapy, the majority prescribed 45-50.4 Gy, and 82.1% used IMRT/VMAT for treatment. For pancreas cancer, neoadjuvant chemotherapy followed by surgery in borderline resectable tumors and induction chemotherapy followed by radical radiotherapy for non-resectable tumors were the most frequent approaches. IMRT/VMAT was the primary technique. Locally advanced rectal cancer treatment is mainly based on neoadjuvant radiotherapy in all institutions. The preferred radiation doses typically range from 45 to 50 Gy in conventional fractionation. IMRT/VMAT was standard in most Institutions.

CONCLUSIONS

Spain's radiotherapy practices among respondents generally align with international guidelines for GI tumors highlighting Spain's commitment to evidence-based medical practice.

摘要

背景

胃肠肿瘤工作组是西班牙放射治疗协会的一个部门,于2020年12月进行了一项调查,以评估西班牙放射肿瘤学家对胃肠道肿瘤国际指南的遵循情况。

材料与方法

我们使用谷歌表单设计了一项涵盖食管癌、胃癌、胰腺癌和直肠癌治疗的调查。

结果

在食管癌治疗中,76.7%的机构采用新辅助放化疗作为标准治疗方法。常规分割放疗剂量范围为41.1至50.4 Gy。83.3%的中心进行了计划正电子发射断层扫描-计算机断层扫描(PET-CT),86.7%的机构首选调强放射治疗/容积弧形调强放疗(IMRT/VMAT)技术。对于胃癌,71.4%的机构遵循围手术期化疗指南。在辅助放疗方面,大多数机构规定的剂量为45-50.4 Gy,82.1%的机构使用IMRT/VMAT进行治疗。对于胰腺癌,对于边界可切除肿瘤,最常用的方法是新辅助化疗后手术;对于不可切除肿瘤,是诱导化疗后根治性放疗。IMRT/VMAT是主要技术。在所有机构中,局部晚期直肠癌的治疗主要基于新辅助放疗。常规分割放疗的首选剂量通常为45至50 Gy。大多数机构以IMRT/VMAT为标准治疗方法。

结论

受访者中西班牙的放疗实践总体上符合胃肠道肿瘤的国际指南,这突出了西班牙对循证医疗实践的承诺。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55f5/11321793/883aae1b22a6/rpor-29-3-340f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55f5/11321793/883aae1b22a6/rpor-29-3-340f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55f5/11321793/883aae1b22a6/rpor-29-3-340f1.jpg

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本文引用的文献

1
Rectal Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.《直肠癌(2022 年第 2 版)》,美国国家综合癌症网络(NCCN)肿瘤学临床实践指南。
J Natl Compr Canc Netw. 2022 Oct;20(10):1139-1167. doi: 10.6004/jnccn.2022.0051.
2
Modern Management of Esophageal Cancer: Radio-Oncology in Neoadjuvancy, Adjuvancy and Palliation.食管癌的现代管理:新辅助、辅助和姑息治疗中的放射肿瘤学
Cancers (Basel). 2022 Jan 15;14(2):431. doi: 10.3390/cancers14020431.
3
Long-term Efficacy of Neoadjuvant Chemoradiotherapy Plus Surgery for the Treatment of Locally Advanced Esophageal Squamous Cell Carcinoma: The NEOCRTEC5010 Randomized Clinical Trial.
新辅助放化疗联合手术治疗局部晚期食管鳞癌的长期疗效:NEOCRTEC5010 随机临床试验。
JAMA Surg. 2021 Aug 1;156(8):721-729. doi: 10.1001/jamasurg.2021.2373.
4
Pancreatic adenocarcinoma.胰腺腺癌
JAAPA. 2020 Nov;33(11):50-51. doi: 10.1097/01.JAA.0000718300.59420.6c.
5
Radiation Therapy for Rectal Cancer: Executive Summary of an ASTRO Clinical Practice Guideline.直肠癌放射治疗:ASTRO 临床实践指南执行摘要。
Pract Radiat Oncol. 2021 Jan-Feb;11(1):13-25. doi: 10.1016/j.prro.2020.08.004. Epub 2020 Oct 21.
6
Basics and Frontiers on Pancreatic Cancer for Radiation Oncology: Target Delineation, SBRT, SIB technique, MRgRT, Particle Therapy, Immunotherapy and Clinical Guidelines.放射肿瘤学中胰腺癌的基础与前沿:靶区勾画、立体定向体部放疗、同步整合加量技术、磁共振引导放疗、粒子治疗、免疫治疗及临床指南
Cancers (Basel). 2020 Jun 29;12(7):1729. doi: 10.3390/cancers12071729.
7
Treatment of Locally Advanced Esophageal Carcinoma: ASCO Guideline.局部晚期食管癌的治疗:ASCO 指南。
J Clin Oncol. 2020 Aug 10;38(23):2677-2694. doi: 10.1200/JCO.20.00866. Epub 2020 Jun 22.
8
Radiation Therapy for Pancreatic Cancer: Executive Summary of an ASTRO Clinical Practice Guideline.放射治疗胰腺癌:ASTRO 临床实践指南执行摘要。
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9
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Radiat Oncol. 2019 May 22;14(1):84. doi: 10.1186/s13014-019-1294-0.
10
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BMC Cancer. 2018 Sep 10;18(1):877. doi: 10.1186/s12885-018-4770-2.