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本文引用的文献

1
Vital Signs: Missed Opportunities for Preventing Congenital Syphilis - United States, 2022.生命体征:错失预防先天梅毒的机会-美国,2022 年。
MMWR Morb Mortal Wkly Rep. 2023 Nov 17;72(46):1269-1274. doi: 10.15585/mmwr.mm7246e1.
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Congenital Syphilis Diagnosed Beyond the Neonatal Period in the United States: 2014-2018.美国超过新生儿期诊断的先天性梅毒:2014-2018 年。
Pediatrics. 2021 Sep;148(3). doi: 10.1542/peds.2020-049080.
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Sexually Transmitted Infections Treatment Guidelines, 2021.《2021年性传播感染治疗指南》
MMWR Recomm Rep. 2021 Jul 23;70(4):1-187. doi: 10.15585/mmwr.rr7004a1.
4
Missed Opportunities for Prevention of Congenital Syphilis - United States, 2018.预防先天性梅毒的错失机会 - 美国,2018 年。
MMWR Morb Mortal Wkly Rep. 2020 Jun 5;69(22):661-665. doi: 10.15585/mmwr.mm6922a1.
5
Screening for Syphilis Infection in Pregnant Women: US Preventive Services Task Force Reaffirmation Recommendation Statement.孕妇梅毒感染筛查:美国预防服务工作组重新确认推荐声明。
JAMA. 2018 Sep 4;320(9):911-917. doi: 10.1001/jama.2018.11785.
6
Untreated maternal syphilis and adverse outcomes of pregnancy: a systematic review and meta-analysis.未经治疗的母体梅毒与妊娠不良结局:系统评价和荟萃分析。
Bull World Health Organ. 2013 Mar 1;91(3):217-26. doi: 10.2471/BLT.12.107623. Epub 2013 Jan 17.
7
Hospitalization cost of congenital syphilis diagnosis from insurance claims data in the United States.美国保险理赔数据中先天性梅毒诊断的住院费用。
Sex Transm Dis. 2013 Mar;40(3):226-9. doi: 10.1097/OLQ.0b013e31827c5b9f.

儿科药剂师在先天性梅毒预防和治疗中的作用。

The Role of Pediatric Pharmacists in the Prevention and Treatment of Congenital Syphilis.

作者信息

Barnes Taylor, Girotto Jennifer E

机构信息

Department of Pharmacy (TB), Orlando Health, Orlando, FL.

Department of Pharmacy Practice (JG), University of Connecticut, Storrs, CT.

出版信息

J Pediatr Pharmacol Ther. 2024 Aug;29(4):429-433. doi: 10.5863/1551-6776-29.4.429. Epub 2024 Aug 13.

DOI:10.5863/1551-6776-29.4.429
PMID:39144389
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11321802/
Abstract

In recent years, rates of syphilis in adults have been on the rise resulting in an increase in the number of neonates born with congenital syphilis. National organizations including the Centers for Disease Control and Prevention as well as The US Preventative Services Task Force recommend routine testing of pregnant persons to identify and provide maternal syphilis treatment prior to delivery. Significant variability exists between states for these screenings, resulting in some pregnant persons not being diagnosed prior to delivery. The Pediatric Pharmacy Association (PPA) believes that pharmacists, along with other health care providers can help by ensuring optimal syphilis testing and treatment pathways for pregnant individuals and newborns are included in their workplaces. PPA also supports pharmacists working to increase treatment compliance by providing medication education and counseling regarding optimal treatment of syphilis infections, as well as work with state and local governments to standardize treatment recommendations.

摘要

近年来,成人梅毒发病率一直在上升,导致先天性梅毒新生儿数量增加。包括疾病控制与预防中心以及美国预防服务工作组在内的国家组织建议对孕妇进行常规检测,以便在分娩前识别并为患有梅毒的孕妇提供治疗。各州在这些筛查方面存在很大差异,导致一些孕妇在分娩前未被诊断出来。儿科药学协会(PPA)认为,药剂师与其他医疗保健提供者可以提供帮助,确保在其工作场所纳入针对孕妇和新生儿的最佳梅毒检测和治疗途径。PPA还支持药剂师通过提供关于梅毒感染最佳治疗方法的用药教育和咨询来努力提高治疗依从性,并与州和地方政府合作使治疗建议标准化。