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持续正压给氧改善模拟颈椎脊髓损伤患者的纤维支气管镜插管效果及安全性:一项前瞻性双盲随机对照研究

Continuous Positive-Pressure Oxygen Supply Improves Fiberoptic Intubation Efficacy and Safety in Patients With Simulated Cervical Spinal Injury: A Prospective Double-Blind Randomized Controlled Study.

作者信息

Qinye Shi, Tianlun Zhu, Youfa Zhou, Gang Chen

机构信息

Anesthesia, Zhejiang University School of Medicine Sir Run Run Shaw Hospital, Hangzhou, CHN.

出版信息

Cureus. 2024 Aug 13;16(8):e66802. doi: 10.7759/cureus.66802. eCollection 2024 Aug.

DOI:10.7759/cureus.66802
PMID:39144416
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11323962/
Abstract

BACKGROUND

Fiberoptic intubation is an important method for tracheal intubation in patients with cervical spine injury. How to effectively and safely complete fiberoptic intubation while maintaining the stability of the cervical spine is very important. This study compared the efficiency and safety of fiberoptic intubation after anesthesia induction under different types of air pressure in patients with simulated cervical spinal injury.

METHODS

In total, 59 adult patients who underwent fiberoptic intubation with a cervical collar for simulated cervical spinal injury were randomly allocated to continuous positive-pressure oxygen, normal-pressure, or intermittent negative-pressure suction groups. After the induction of anesthesia and adequate 100% oxygenation, which confirmed effective neuromuscular blockade, it was deemed appropriate to begin fiberoptic intubation. In the continuous positive-pressure oxygen group, the fiberoptic device was connected through the negative-pressure suction path with 5 L/min oxygen. In the intermittent negative-pressure suction group, the fiberoptic device was connected to the negative-pressure suction device. In the normal-pressure group, the flexible fiberoptic device was not connected to either the oxygen source or the negative-pressure suction device. The intubation time was recorded as the primary outcome measure. The intubation success rate, number of attempts, minimum SpO2, objective lens contamination rate, and incidence of complications were also compared among the groups.

RESULTS

Compared with those in the other groups, the median (range) intubation time in the continuous positive-pressure group was 59 (36-181) seconds, which was significantly shorter than that in the normal-pressure group, 167 (46-181) seconds, and the intermittent negative-pressure suction group, 132.5 (38-181) seconds (P=0.04). The success rate of nasotracheal intubation was significantly greater in the continuous positive-pressure group (94.7%, 18/19) than in the normal-pressure group (50%, 10/20) and intermittent negative-pressure suction group (50%, 10/20) (P=0.004). There was a significant difference among the three groups (P=0.043). The median (range) minimum SpO2 during fiberoptic intubation was 100% (99-100%) in the continuous positive-pressure group, 100% (90-100%) in the normal-pressure group, and 99% (88-100%) in the intermittent negative-pressure suction group (P=0.029). However, no statistically significant difference was detected among the groups with complications.

CONCLUSION

The continuous use of positive-pressure oxygen via the negative-pressure suction pathway can improve the efficiency and safety of fiberoptic intubation in patients with simulated cervical spinal injury after anesthesia induction.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c59/11323962/ba61e0f26cde/cureus-0016-00000066802-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c59/11323962/f02e1d2d4955/cureus-0016-00000066802-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c59/11323962/ba61e0f26cde/cureus-0016-00000066802-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c59/11323962/f02e1d2d4955/cureus-0016-00000066802-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c59/11323962/ba61e0f26cde/cureus-0016-00000066802-i02.jpg

背景

纤维支气管镜引导插管是颈椎损伤患者气管插管的重要方法。如何在维持颈椎稳定性的同时有效且安全地完成纤维支气管镜引导插管非常重要。本研究比较了模拟颈椎损伤患者在不同气压类型下麻醉诱导后纤维支气管镜引导插管的效率和安全性。

方法

总共59例佩戴颈托进行模拟颈椎损伤纤维支气管镜引导插管的成年患者被随机分配至持续正压给氧组、常压组或间歇负压吸引组。在麻醉诱导及充分的100%氧合(确认有效神经肌肉阻滞)后,认为适宜开始纤维支气管镜引导插管。在持续正压给氧组,纤维支气管镜设备通过负压吸引通道连接,氧流量为5L/min。在间歇负压吸引组,纤维支气管镜设备连接至负压吸引装置。在常压组,可弯曲纤维支气管镜设备未连接氧源或负压吸引装置。记录插管时间作为主要结局指标。还比较了各组间的插管成功率、尝试次数、最低血氧饱和度、物镜污染率及并发症发生率。

结果

与其他组相比,持续正压组的中位(范围)插管时间为59(36 - 181)秒,显著短于常压组的167(46 - 181)秒和间歇负压吸引组的132.5(38 - 181)秒(P = 0.04)。持续正压组经鼻气管插管成功率(94.7%,18/19)显著高于常压组(50%,10/20)和间歇负压吸引组(50%,10/20)(P = 0.004)。三组间存在显著差异(P = 0.043)。纤维支气管镜引导插管期间最低血氧饱和度的中位(范围)值在持续正压组为100%(99 - 100%),常压组为100%(90 - 100%),间歇负压吸引组为99%(88 - 100%)(P = 0.029)。然而,各组间并发症发生率无统计学显著差异。

结论

通过负压吸引通道持续给予正压氧可提高模拟颈椎损伤患者麻醉诱导后纤维支气管镜引导插管的效率和安全性。

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本文引用的文献

1
Cause of Death Trends Among Persons With Spinal Cord Injury in the United States: 1960-2017.美国脊髓损伤患者死因趋势:1960-2017 年。
Arch Phys Med Rehabil. 2022 Apr;103(4):634-641. doi: 10.1016/j.apmr.2021.09.019. Epub 2021 Nov 18.
2
2022 American Society of Anesthesiologists Practice Guidelines for Management of the Difficult Airway.2022 年美国麻醉医师学会困难气道管理实践指南。
Anesthesiology. 2022 Jan 1;136(1):31-81. doi: 10.1097/ALN.0000000000004002.
3
Supraglottic jet oxygenation and ventilation reduces desaturation during bronchoscopy under moderate to deep sedation with propofol and remifentanil: A randomised controlled clinical trial.
声门上喷射氧气通气在丙泊酚和瑞芬太尼中度至深度镇静下支气管镜检查中减少低氧血症:一项随机对照临床试验。
Eur J Anaesthesiol. 2021 Mar 1;38(3):294-301. doi: 10.1097/EJA.0000000000001401.
4
Utility of oxygen insufflation through working channel during fiberoptic intubation in apneic patients: a prospective randomized controlled study.在窒息患者的纤维支气管镜插管中通过工作通道进行氧气吹入的效用:一项前瞻性随机对照研究。
BMC Anesthesiol. 2020 Nov 10;20(1):282. doi: 10.1186/s12871-020-01201-9.
5
Difficult Airway Society guidelines for awake tracheal intubation (ATI) in adults.困难气道学会成人清醒气管插管指南。
Anaesthesia. 2020 Apr;75(4):509-528. doi: 10.1111/anae.14904. Epub 2019 Nov 14.
6
Oxygen insufflation working channel in a fiberscope is a useful method: A case report and review of literature.纤维内镜氧气注入工作通道是一种有用的方法:病例报告及文献复习
World J Clin Cases. 2018 Dec 26;6(16):1189-1193. doi: 10.12998/wjcc.v6.i16.1189.
7
Rescue transtracheal jet ventilation during difficult intubation in patients with upper airway cancer.抢救性经气管喷射通气在气道上段癌患者困难插管中的应用。
Anaesth Crit Care Pain Med. 2018 Dec;37(6):539-544. doi: 10.1016/j.accpm.2017.10.005. Epub 2017 Nov 10.
8
The Shikani Optical Stylet as an Alternative to Awake Fiberoptic Intubation in Patients at Risk of Secondary Cervical Spine Injury: A Randomized Controlled Trial.Shikani 光导芯在有继发颈椎损伤风险的患者中替代清醒纤维光插管:一项随机对照试验。
J Neurosurg Anesthesiol. 2018 Oct;30(4):354-358. doi: 10.1097/ANA.0000000000000454.
9
A prospective cohort study of awake fibreoptic intubation practice at a tertiary centre.一项在三级中心进行的清醒纤维支气管镜插管实践的前瞻性队列研究。
Anaesthesia. 2017 Jun;72(6):694-703. doi: 10.1111/anae.13844.
10
A Retrospective Study of Success, Failure, and Time Needed to Perform Awake Intubation.一项关于清醒插管成功率、失败率及所需时间的回顾性研究。
Anesthesiology. 2016 Jul;125(1):105-14. doi: 10.1097/ALN.0000000000001140.