Lee In-Kyu, Park Na-Youn, Park So Young, Jeong JunHyeok, Lee Jisu, Moon Bokyung, Kim Young-Suk, Kim Junghoan, Kho Younglim
Department of Food Technology & Service, Eulji University, Seongnam-si, Gyeonggi-do 13135 Korea.
Department of Health, Environment & Safety, Eulji University, Seongnam-si, Gyeonggi-do 13135 Korea.
Food Sci Biotechnol. 2024 Jul 10;33(10):2417-2426. doi: 10.1007/s10068-024-01651-8. eCollection 2024 Jul.
This study investigated the presence of nitrosamines, known carcinogens, in 1320 food samples from South Korea using LC-APCI-MS/MS analysis. Results showed nitrosamines were detected in 72% of samples, with processed foods exhibiting higher levels. Sesame oil, snow white rice cake, fried chicken wings, and fried squid were identified as having the highest nitrosamine content. Daily intake estimates revealed nitrosodiethylamine (NDEA), nitrosodibutylamine (NDBA), and nitrosopyrrolidine (NPYR) as major contributors to exposure. Risk assessment, based on BMDL10 values and MOE calculations, indicated low health risks overall, but certain food groups at the 95th percentile showed MOEs below the safety threshold, warranting attention. This underscores the need for ongoing monitoring and regulation of nitrosamine levels in food products to protect public health, particularly in regions with high consumption of processed foods like South Korea. Further research and regulatory measures are crucial to minimize nitrosamine exposure and mitigate associated health risks.
The online version contains supplementary material available at 10.1007/s10068-024-01651-8.
本研究使用液相色谱-大气压化学电离质谱/质谱分析法，对来自韩国的1320份食品样本中已知致癌物亚硝胺的存在情况进行了调查。结果显示，72%的样本中检测到了亚硝胺，加工食品中的含量更高。芝麻油、雪白米糕、炸鸡翅和炸鱿鱼被确定为亚硝胺含量最高的食品。每日摄入量估计表明，二乙基亚硝胺（NDEA）、二丁基亚硝胺（NDBA）和亚硝基吡咯烷（NPYR）是主要的暴露源。基于BMDL10值和MOE计算的风险评估表明，总体健康风险较低，但第95百分位数的某些食品组的MOE低于安全阈值，值得关注。这凸显了持续监测和监管食品中亚硝胺水平以保护公众健康的必要性，特别是在像韩国这样加工食品消费量高的地区。进一步的研究和监管措施对于尽量减少亚硝胺暴露和降低相关健康风险至关重要。
在线版本包含可在10.1007/s10068-024-01651-8获取的补充材料。
