• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

凝固在时间里：成熟囊性畸胎瘤恶变的术中诊断与处理

Frozen in Time: Intraoperative Diagnosis and Management of Malignant Transformation in Mature Cystic Teratoma.

作者信息

Sanap Arun Sudhakar, Davile Medha D, Kamath Anusha A, Mundle Shuchita R

机构信息

Department of Obstetrics and Gynecology, AIIMS, Nagpur, Maharashtra, India.

出版信息

J Midlife Health. 2024 Apr-Jun;15(2):115-118. doi: 10.4103/jmh.jmh_253_23. Epub 2024 Jul 5.

DOI:10.4103/jmh.jmh_253_23
PMID:39145267
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11321514/
Abstract

Malignant transformation (MCT) of ovary is rare complications affecting elderly, squamous cell carcinoma being the most common. The prognosis worsens with extraovarian spread. We present two cases of MCT-derived SCC. Patients exhibited abdominal lump, pain, bowel symptoms, sometimes with weight loss; imaging revealed MCT. Age (51-60), postmenopausal status, large size (>20 cm), bilaterality, and complex ovarian lesions raised suspicion of malignancy. Elevated tumor markers (e.g., cancer antigen-125 and lactate dehydrogenase) were noted in one case. Intraoperative frozen section confirmed malignancy, guiding staging laparotomy. One case was advanced stage on histopathology. Intraoperative frozen section aids optimal staging.

摘要

卵巢恶性转化（MCT）是影响老年人的罕见并发症，其中鳞状细胞癌最为常见。随着卵巢外扩散，预后会恶化。我们报告了两例源自MCT的鳞状细胞癌（SCC）病例。患者表现为腹部肿块、疼痛、肠道症状，有时伴有体重减轻；影像学检查显示为MCT。年龄（51 - 60岁）、绝经后状态、大尺寸（>20 cm）、双侧性以及复杂的卵巢病变增加了恶性肿瘤的怀疑。在一例病例中发现肿瘤标志物（如癌抗原-125和乳酸脱氢酶）升高。术中冰冻切片确诊为恶性肿瘤，指导分期剖腹手术。一例在组织病理学上为晚期。术中冰冻切片有助于进行最佳分期。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/11321514/ceb7510cfffd/JMH-15-115-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/11321514/e7a58b57fa79/JMH-15-115-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/11321514/212b1afae5b9/JMH-15-115-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/11321514/ceb7510cfffd/JMH-15-115-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/11321514/e7a58b57fa79/JMH-15-115-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/11321514/212b1afae5b9/JMH-15-115-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0480/11321514/ceb7510cfffd/JMH-15-115-g003.jpg

相似文献

1
Frozen in Time: Intraoperative Diagnosis and Management of Malignant Transformation in Mature Cystic Teratoma.凝固在时间里：成熟囊性畸胎瘤恶变的术中诊断与处理
J Midlife Health. 2024 Apr-Jun;15(2):115-118. doi: 10.4103/jmh.jmh_253_23. Epub 2024 Jul 5.
2
Squamous cell carcinoma in mature cystic teratoma of the ovary induced by human papillomavirus 16 infection: A case report and literature review.卵巢成熟囊性畸胎瘤中由人乳头瘤病毒 16 感染引起的鳞状细胞癌：病例报告及文献复习。
Medicine (Baltimore). 2022 Sep 23;101(38):e30667. doi: 10.1097/MD.0000000000030667.
3
Relevance of frozen sections and serum markers in invasive squamous cell carcinoma arising from ovarian mature cystic teratoma: two case reports.冰冻切片和血清标志物在卵巢成熟囊性畸胎瘤来源的浸润性鳞状细胞癌中的相关性：两例报告
J Med Case Rep. 2016 Jan 22;10:20. doi: 10.1186/s13256-015-0783-5.
4
Malignant transformation in mature cystic teratoma of the ovary: a retrospective study of eight cases and review of literature.卵巢成熟性囊性畸胎瘤的恶性转化：8例回顾性研究及文献复习
Prz Menopauzalny. 2018 Jun;17(2):63-68. doi: 10.5114/pm.2018.77304. Epub 2018 Jun 30.
5
[Clinical analysis of 44 cases with malignant transformation of ovarian mature cystic teratoma].44例卵巢成熟囊性畸胎瘤恶变的临床分析
Zhonghua Fu Chan Ke Za Zhi. 2013 Feb;48(2):123-8.
6
A rare case of squamous cell carcinoma transformation in a mature cystic teratoma of the ovary.卵巢成熟囊性畸胎瘤发生鳞状细胞癌转化的罕见病例。
SAGE Open Med Case Rep. 2023 Aug 12;11:2050313X231193305. doi: 10.1177/2050313X231193305. eCollection 2023.
7
A rare case of squamous cell carcinoma associated with a huge ovarian dermoid cyst in a postmenopausal woman.一名绝经后女性患鳞状细胞癌并伴有巨大卵巢皮样囊肿的罕见病例。
Prz Menopauzalny. 2023 Sep;22(3):169-172. doi: 10.5114/pm.2023.131456. Epub 2023 Sep 25.
8
Clinical significance of combined use of macrophage colony-stimulating factor and squamous cell carcinoma antigen as a selective diagnostic marker for squamous cell carcinoma arising in mature cystic teratoma of the ovary.联合使用巨噬细胞集落刺激因子和鳞状细胞癌抗原作为卵巢成熟性囊性畸胎瘤中鳞状细胞癌的选择性诊断标志物的临床意义。
Gynecol Oncol. 2000 Jun;77(3):405-9. doi: 10.1006/gyno.2000.5784.
9
Squamous cell carcinoma arising from mature cystic teratoma of the ovary.卵巢成熟囊性畸胎瘤恶变的鳞状细胞癌。
Int J Gynecol Cancer. 2011 Apr;21(3):466-74. doi: 10.1097/IGC.0b013e31820d3e5b.
10
Malignant transformation arising from mature ovarian cystic teratoma: A case series.成熟性卵巢囊性畸胎瘤恶变：病例系列。
Medicine (Baltimore). 2021 Apr 2;100(13):e24726. doi: 10.1097/MD.0000000000024726.

本文引用的文献

1
Clinicopathological observation of mature teratoma with malignant transformation, a single center retrospective study.成熟畸胎瘤恶变的临床病理观察：一项单中心回顾性研究。
Indian J Pathol Microbiol. 2022 Apr-Jun;65(2):369-373. doi: 10.4103/IJPM.IJPM_828_20.
2
Malignant Degeneration of a Mature Ovarian Teratoma.成熟卵巢畸胎瘤的恶性变
Case Rep Obstet Gynecol. 2021 Jul 22;2021:5527467. doi: 10.1155/2021/5527467. eCollection 2021.
3
Malignant transformation arising from mature ovarian cystic teratoma: A case series.成熟性卵巢囊性畸胎瘤恶变：病例系列。
Medicine (Baltimore). 2021 Apr 2;100(13):e24726. doi: 10.1097/MD.0000000000024726.
4
Are Ovarian Dermoid Cysts Should Be Always Considered Benign? A Case Series Study of Different Malignant Transformation.卵巢皮样囊肿是否应始终被视为良性？不同恶性转化的病例系列研究
Indian J Surg Oncol. 2020 Sep;11(Suppl 2):156-158. doi: 10.1007/s13193-020-01159-7. Epub 2020 Jul 4.
5
Squamous cell carcinoma transformation in mature cystic teratoma of the ovary: a systematic review.卵巢成熟囊性畸胎瘤中的鳞状细胞癌转化：系统评价。
BMC Cancer. 2019 Mar 11;19(1):217. doi: 10.1186/s12885-019-5393-y.
6
Detection of human papillomavirus in squamous cell carcinoma arising from dermoid cysts.皮样囊肿来源的鳞状细胞癌中人乳头瘤病毒的检测
Taiwan J Obstet Gynecol. 2015 Oct;54(5):559-66. doi: 10.1016/j.tjog.2015.08.008.
7
Malignancy associated with ovarian teratomas: frequency, histotypes, and diagnostic accuracy of intraoperative consultation.与卵巢畸胎瘤相关的恶性肿瘤：术中会诊的频率、组织学类型及诊断准确性
Ann Diagn Pathol. 2015 Jun;19(3):103-6. doi: 10.1016/j.anndiagpath.2015.02.004. Epub 2015 Feb 28.
8
Squamous carcinoma of the ovary.卵巢鳞状细胞癌。
Curr Oncol Rep. 2014 Dec;16(12):413. doi: 10.1007/s11912-014-0413-1.
9
Malignant transformation in a mature teratoma with metastatic deposits in the omentum: a case report.成熟畸胎瘤发生恶性转化并伴有大网膜转移瘤：一例报告
Case Rep Pathol. 2012;2012:568062. doi: 10.1155/2012/568062. Epub 2012 Oct 3.
10
Malignant transformation arising from mature cystic teratoma of the ovary: a retrospective study of 20 cases.卵巢成熟囊性畸胎瘤恶变 20 例回顾性研究。
Int J Gynecol Cancer. 2010 Jul;20(5):766-71. doi: 10.1111/igc.0b013e3181daaf1d.