Mahtate Mariam, Talib Sarah, Slaoui Aziz, Zeraidi Najia, Lakhdar Amina, Rhrab Brahim, Baydada Aziz
Gynecology-Obstetrics and Endoscopy Department, Maternity Souissi, University Hospital Center IBN SINA, University Mohammed V, Rabat, Morocco.
Gynecology-Obstetrics and Endocrinology Department, Maternity Souissi, University Hospital Center IBN SINA, University Mohammed V, Rabat, Morocco.
Case Rep Obstet Gynecol. 2021 Jul 22;2021:5527467. doi: 10.1155/2021/5527467. eCollection 2021.
Mature cystic teratoma is the most common type of ovarian germ cell neoplasm, but occasionally, it can undergo malignant transformations, especially in postmenopausal women. These secondary malignant neoplasms are most commonly squamous cell carcinomas. The absence of clinical and radiological specificity of this transformation means that the diagnosis remains purely histological. Data is insufficient regarding the appropriate management given their rarity. However, the treatment is multidisciplinary and is based on surgery and a platinum-based chemotherapy regimen. We report the case of a 53-year-old postmenopausal female patient with malignant transformation of the ovarian teratoma who was treated surgically and whose outcome was favorable. The diagnosis of the teratoma was evoked on imaging, while the diagnosis of squamous cell carcinoma was revealed on histology. Malignant transformation is an uncommon complication of mature ovarian teratomas. No clinical, radiological, or biological sign is specific; therefore, resection of any ovarian mass, even asymptomatic, is required.
成熟囊性畸胎瘤是卵巢生殖细胞肿瘤最常见的类型，但偶尔会发生恶性转化，尤其是在绝经后女性中。这些继发性恶性肿瘤最常见的是鳞状细胞癌。这种转化缺乏临床和影像学特异性，这意味着诊断仍完全依赖组织学。鉴于其罕见性，关于适当治疗的数据不足。然而，治疗是多学科的，基于手术和铂类化疗方案。我们报告一例53岁绝经后女性患者，其卵巢畸胎瘤发生恶性转化，接受了手术治疗，预后良好。影像学检查提示畸胎瘤诊断，组织学检查确诊为鳞状细胞癌。恶性转化是成熟卵巢畸胎瘤的一种罕见并发症。没有临床、影像学或生物学特征具有特异性；因此，即使是无症状的卵巢肿块也需要切除。
