Mathur S, Genco P V, Møller B, Mårdh P A
J Reprod Immunol. 1985 Dec;8(4):353-8. doi: 10.1016/0165-0378(85)90010-5.
Hemagglutinating antibodies to Mycoplasma hominis were present in 30 of 83 infertile, 15 of 40 pregnant and 5 of 20 post-partum females and 20 of 82 infertile males in contrast to only 2 of 21 fertile females and 5 of 25 fertile males. Their presence correlated with sperm antibody detection by TAT in Lab. 4, the immunobead-binding assay of Lab. 1 and the SIT of Lab. 11, but not with other sperm antibody assays. Immunofluorescent antibodies to Chlamydia trachomatis, on the other hand, did not correlate with the incidence of sperm antibodies. Among 305 serum samples tested, 12 were positive for testicular antibodies, 8 had antibodies to kidney, 7 to ovary and 15 to endometrium. A majority of serum samples positive for antibodies to testis and ovary, but not endometrium, reacted against sperm in different assays. Eight of 135 samples tested had antibodies to human leukocyte antigenic HLA-Aw19 (Aw19, A28, A29, A30 and A32) and/or B35 (B35, B5 and B15) complexes. Six of these samples were also positive for sperm antibodies by one or more antibody assays. Cross-reactive antigens may be present in sperm, M. hominis, testis, ovary and leukocytes.
83名不孕女性中有30名、40名怀孕女性中有15名、20名产后女性中有5名以及82名不孕男性中有20名存在人型支原体血凝抗体，相比之下，21名可育女性中只有2名、25名可育男性中只有5名存在该抗体。这些抗体的存在与实验室4的TAT精子抗体检测、实验室1的免疫珠结合试验以及实验室11的精子免疫试验结果相关，但与其他精子抗体检测方法无关。另一方面，沙眼衣原体免疫荧光抗体与精子抗体的发生率无关。在检测的305份血清样本中，12份睾丸抗体呈阳性，8份有肾脏抗体，7份有卵巢抗体，15份有子宫内膜抗体。大多数睾丸和卵巢抗体呈阳性但子宫内膜抗体阴性的血清样本在不同检测中与精子发生反应。在检测的135份样本中，有8份含有针对人类白细胞抗原HLA-Aw19（Aw19、A28、A29、A30和A32）和/或B35（B35、B5和B15）复合物的抗体。其中6份样本通过一种或多种抗体检测精子抗体也呈阳性。交叉反应抗原可能存在于精子、人型支原体、睾丸、卵巢和白细胞中。
