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羟基磷灰石陶瓷涂层股骨柄在初次全髋关节置换术中的结果:来自英国单一中心的优秀生存率报告。

Outcomes of a hydroxyapatite ceramic-coated femoral stem in primary total hip arthroplasty: a report of excellent survivorship from a single United Kingdom centre.

作者信息

Abdelghafour Karim M, Khaled Sherif A, Abdel-Kader Khaled F M, Azeem Hazem A, Shah Nirav N

机构信息

Worthing Hospital, University Hospitals of Sussex, Lyndhurst Road, Worthing BN112DH, UK - Kasr Alainy School of Medicine Cairo University, Al-Saray Street, El Manial Cairo 11956, Egypt.

Kasr Alainy School of Medicine Cairo University, Al-Saray Street, El Manial Cairo 11956, Egypt.

出版信息

SICOT J. 2024;10:28. doi: 10.1051/sicotj/2024026. Epub 2024 Aug 14.

Abstract

BACKGROUND

Hydroxyapatite (HA) coated femoral stems were introduced to enhance the biological fixation at the implant-bone interface, aiming to increase the longevity and survival of the prostheses. We aimed to assess the long-term outcomes of an HA ceramic (HAC) coated stem in primary total hip arthroplasty (THA), assess the stem survival, and clinically evaluate the patients using patient-reported outcome measures (PROMs) and radiological evaluation of stem osseointegration.

PATIENTS AND METHODS

This was a prospective evaluation of a retrospective cohort of 385 patients (442 hips) who underwent primary THA between June 2008 and December 2018. The mean age was 63.83 years (range, 30-82 years). During the follow-up duration, 23 patients died, and 36 patients (38 hips) were lost to follow-up. Prospective data collected for 326 patients (381 hips) was used to evaluate stem survival with the Kaplan-Meier method using aseptic loosening or any revision as the endpoint. Clinical evaluation was done using the EuroQol five-dimension (EQ-5D) scoring system and PROMs using the Oxford Hip Score (OHS) and Merle D'Aubigne Postel (MDP) score. Radiological assessments were performed using the Engh radiological criteria for stem osteointegration.

RESULTS

The mean follow-up duration was 9.39 years (range, 4-14.5 years). The survival of the HAC-coated femoral stem was 100% (95% confidence interval [CI], 96.7-100%) at 14 years with aseptic loosening as the endpoint, and 98.9% (CI, 96.7-100%) at 14 years with stem revision for any reason as the endpoint. The mean OHS was 44.5 (range, 30-48), and the mean MDP score was 15.87 (range, 10-18). Radiological evaluations showed full osseointegration of all stems.

CONCLUSION

This HAC-coated femoral stem has shown excellent survivorship, functional outcomes, and full osseointegration at the final follow-up.

摘要

背景

羟基磷灰石(HA)涂层股骨柄被引入以增强植入物与骨界面的生物固定,旨在提高假体的使用寿命和生存率。我们旨在评估HA陶瓷(HAC)涂层柄在初次全髋关节置换术(THA)中的长期疗效,评估柄的生存率,并使用患者报告结局指标(PROMs)和柄骨整合的影像学评估对患者进行临床评估。

患者与方法

这是一项对2008年6月至2018年12月期间接受初次THA的385例患者(442髋)的回顾性队列进行的前瞻性评估。平均年龄为63.83岁(范围30 - 82岁)。在随访期间,23例患者死亡,36例患者(38髋)失访。收集的326例患者(381髋)的前瞻性数据用于采用Kaplan-Meier法评估柄的生存率,以无菌性松动或任何翻修为终点。临床评估采用欧洲五维健康量表(EQ-5D)评分系统,PROMs采用牛津髋关节评分(OHS)和Merle D'Aubigne Postel(MDP)评分。影像学评估采用Engh柄骨整合影像学标准。

结果

平均随访时间为9.39年(范围4 - 14.5年)。以无菌性松动为终点,14年时HAC涂层股骨柄的生存率为100%(95%置信区间[CI],96.7 - 100%);以任何原因进行柄翻修为终点,14年时生存率为98.9%(CI,96.7 - 100%)。平均OHS为44.5(范围30 - 48),平均MDP评分为15.87(范围10 - 18)。影像学评估显示所有柄均实现完全骨整合。

结论

这种HAC涂层股骨柄在最终随访时显示出优异的生存率、功能结局和完全骨整合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7028/11325862/65a45f613fad/sicotj-10-28-fig1.jpg

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