生物标本研究与法律。

Biospecimen research and the law.

机构信息

Timothy D. Dye is a professor in the Departments of Obstetrics and Gynecology, Pediatrics, Dentistry, and Public Health, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.

Jerry A. Menikoff is a professor at the Centre for Biomedical Ethics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

出版信息

Science. 2024 Aug 16;385(6710):695. doi: 10.1126/science.ads3190. Epub 2024 Aug 15.

DOI:10.1126/science.ads3190

PMID:39146400

Abstract

In the well-known case of Henrietta Lacks, cells from her tumor were taken without consent and used more than 70 years ago to create the first immortal human cell line ("HeLa" cells). That event led to many scientific breakthroughs and to the debate about the ethics of consent and requirements for compensation. May 2024 saw two decisions by US federal courts-one related to Lacks-that could narrow the scope of research allowed on tissues obtained without consent and on nonidentified tissues, with implications for biomedicine.

摘要

在著名的 Henrietta Lacks 案例中，未经同意就从她的肿瘤中提取了细胞，并在 70 多年前用于创建第一个永生的人类细胞系（“HeLa”细胞）。这一事件导致了许多科学突破，并引发了关于同意和赔偿要求的伦理辩论。2024 年 5 月，美国联邦法院做出了两项与 Lacks 有关的裁决，这可能会缩小在未经同意获得的组织和未识别组织上进行研究的范围，这对生物医学有影响。