酒精使用障碍住院患者认知障碍的预测因素。
Predictive factors of cognitive impairment in alcohol use disorder inpatients.
机构信息
Unité de Traitement Ambulatoire des Maladies Addictives, Département d'Addictologie et de Psychiatrie, Hôpital Beaujon, APHP GHU Nord, 100 bd du général Leclerc, 92110 Clichy, France; ResAlCog (Réseau pour la prise en charge des troubles cognitifs liés à l'alcool), 51 bis Rue des Epinettes, 75017 Paris, France.
ResAlCog (Réseau pour la prise en charge des troubles cognitifs liés à l'alcool), 51 bis Rue des Epinettes, 75017 Paris, France; Département de Psychiatrie et de Médecine Addictologique, Site Lariboisière Fernand-Widal, APHP GHU Nord, 200 rue du faubourg Saint-Denis, 75010 Paris, France; UFR de Médecine, Université Paris Cité, 85 boulevard Saint-Germain, 75006 Paris, France; UMRS-1144 Optimisation thérapeutique en neuropsychopharmacologie, Inserm, Université Paris Cité, 4 avenue de l'Observatoire, 75006 Paris, France; FHU Network of Research in Substance Use Disorders (NOR-SUD), 4 avenue de l'Observatoire, 75006 Paris , France.
出版信息
Addict Behav. 2024 Nov;158:108132. doi: 10.1016/j.addbeh.2024.108132. Epub 2024 Aug 13.
BACKGROUND
Cognitive impairments are common in patients with AUD and worsen the prognosis of addiction management. There are no clear guidelines for screening cognitive impairments in hospitalized patients with AUD.
METHODS
Fifty-seven patients with an AUD history who were admitted to an acute hospital and assessed by the addiction care team were included. Those patients were screened for cognitive impairments using the Montreal Cognitive Assessment (MoCA) test. We collected clinical information regarding addiction history, comorbidities, and current treatments. Chi-square tests, t-tests, and Mann-Whitney tests were performed to determine factors associated with a pathological MoCA score (<26).
RESULTS
A pathological MoCA score was positively associated with spatial-temporal disorientation, difficulty in recalling addiction history, patient underreporting of AUD and a date of last alcohol consumption lower than 11 days ago, and negatively associated with a reason for hospitalization due to alcohol-related health issues. No medication was associated with cognitive impairments.
CONCLUSIONS
Clinical elements from assessment by the addiction care team allow for relevant indication for screening cognitive impairments.
背景
认知障碍在 AUD 患者中很常见，并且会使成瘾管理的预后恶化。目前尚无明确的指南用于筛查住院 AUD 患者的认知障碍。
方法
共纳入 57 名因 AUD 住院并接受成瘾护理团队评估的患者。这些患者使用蒙特利尔认知评估（MoCA）测试筛查认知障碍。我们收集了与成瘾史、合并症和当前治疗相关的临床信息。采用卡方检验、t 检验和曼-惠特尼检验来确定与病理性 MoCA 评分（<26）相关的因素。
结果
病理性 MoCA 评分与时空定向障碍、回忆成瘾史困难、患者对 AUD 的漏报以及上次饮酒日期早于 11 天呈正相关，与因酒精相关健康问题住院的原因呈负相关。没有药物与认知障碍相关。
结论
成瘾护理团队评估的临床要素可提示筛查认知障碍的相关指征。
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