Unit of Integrative Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Unit of Integrative Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
J Affect Disord. 2024 Nov 1;364:132-138. doi: 10.1016/j.jad.2024.08.032. Epub 2024 Aug 13.
Premenstrual disorders (PMDs) affect women's quality of life, yet the impact on romantic relationships remains unclear. This study aimed to examine the association between severe PMDs and relationship disruption and initiation.
We conducted a prospective cohort study of 15,606 women during 2009-2021 in Sweden. PMDs were assessed with the modified Premenstrual Symptom Screening Tool at baseline (one-time retrospective self-report), while relationship status was obtained from national population registers during follow-up. Poisson regression was employed to assess the risk of relationship change.
At baseline (mean age 33.5 years), 1666 (10.6 %) women met the criteria for severe PMDs. All women were followed for 9.1 years on average for any change of relationship status. Among married/cohabiting women, PMDs were positively associated with relationship disruption (Incidence risk ratio, IRR =1.21, 95 % CI: 1.01-1.43, p = 0.03). A more pronounced association was suggested for premenstrual dysphoric disorder (IRR = 1.22, 95 % CI: 1.01-1.45, p = 0.03) than severe premenstrual syndrome (IRR = 1.01, 95 % CI: 0.43-1.96, p = 0.98) and among women without depression/anxiety (IRR = 1.21, 95 % CI: 1.00-1.47, p < 0.05) than among those with (IRR = 0.99, 95 % CI: 0.61-1.54 p = 0.96) and IRR = 1.01, 95 % CI: 0.57-1.72, p = 0.97). Among single women, a null association was found between PMDs and relationship initiation (IRR = 1.05, 95 % CI: 0.95-1.15, p = 0.32).
PMDs were not assessed using prospective symptom charting.
Married/cohabiting women with probable severe PMDs have an increased risk of relationship disruption. PMDs were not associated with relationship initiation in single women. Healthcare professionals should recognize relationship challenges in women with severe PMDs, and they may require support to maintain healthy relationships.
经前期障碍（PMD）会影响女性的生活质量，但对恋爱关系的影响仍不清楚。本研究旨在探讨严重 PMD 与关系破裂和开始的关系。
我们在瑞典于 2009-2021 年进行了一项前瞻性队列研究，共有 15606 名女性参与。在基线时（一次性回顾性自我报告）使用改良经前期症状筛查工具评估 PMD，而关系状况则通过随访期间的国家人口登记册获得。采用泊松回归评估关系变化的风险。
在基线时（平均年龄 33.5 岁），1666 名（10.6%）女性符合严重 PMD 的标准。所有女性平均随访 9.1 年，观察任何关系状态的变化。在已婚/同居的女性中，PMD 与关系破裂呈正相关（发病率风险比，IRR=1.21，95%CI：1.01-1.43，p=0.03）。对于经前期烦躁障碍（IRR=1.22，95%CI：1.01-1.45，p=0.03），这种关联比严重经前期综合征（IRR=1.01，95%CI：0.43-1.96，p=0.98）更为明显，对于没有抑郁/焦虑的女性（IRR=1.21，95%CI：1.00-1.47，p<0.05）比有抑郁/焦虑的女性（IRR=0.99，95%CI：0.61-1.54，p=0.96）和 IRR=1.01，95%CI：0.57-1.72，p=0.97）更为明显。对于单身女性，PMD 与关系开始之间没有关联（IRR=1.05，95%CI：0.95-1.15，p=0.32）。
PMD 并未通过前瞻性症状图表进行评估。
患有严重 PMD 的已婚/同居女性发生关系破裂的风险增加。在单身女性中，PMD 与关系开始无关。医疗保健专业人员应认识到患有严重 PMD 的女性所面临的关系挑战，她们可能需要支持以维持健康的关系。
