Fukushima Medical Center for Children and Women, Fukushima Medical University, Fukushima, Japan.
Department of Obstetrics and Gynecology, Tokyo Dental College Ichikawa General Hospital, Chiba, Japan.
J Obstet Gynaecol. 2024 Dec;44(1):2378440. doi: 10.1080/01443615.2024.2378440. Epub 2024 Jul 16.
In the classification of premenstrual disorders (PMDs), premenstrual exacerbation (PME) is listed as one of the variants of PMDs, along with core PMD. However, the incidence of PME and its impact on mental health and quality of life have not been investigated. Therefore, we investigated the proportion of PME among women seeking treatment for premenstrual symptoms in Japan and compared the levels of anxiety, depression and quality of life between women with PME and those with core PMD.
Women who presented to the Department of Obstetrics and Gynaecology of a single institute for treatment of premenstrual symptoms and were diagnosed with PMDs using patient diaries were included in the study. Based on the diagnosis, patients were divided into two groups (core PMD and PME) and their responses to a questionnaire on mental health and quality of life at the first visit were analysed.
A total of 32 women were diagnosed with PMDs (22 with core PMD and 10 with PME). All underlying medical conditions in women with PME were psychiatric disorders. There were no significant differences in various factors between the two groups. In terms of mental health, the PME group had higher levels of anxiety and depression than the core PMD group. Regarding quality of life, the PME group had lower scores than the core PMD group in all domains except physical and social functioning.
Patients seeking treatment for premenstrual symptoms included many PME. Women with PME were more anxious and depressed than those with core PMD, and their quality of life was low in both physical and psychological domains. Patients with PME should be diagnosed and treated more appropriately.
在经前期障碍（PMD）的分类中，经前期恶化（PME）被列为 PMD 的一种变异，与核心 PMD 并列。然而，PME 的发生率及其对心理健康和生活质量的影响尚未得到研究。因此，我们调查了在日本因经前期症状就诊的女性中 PME 的比例，并比较了 PME 女性与核心 PMD 女性之间的焦虑、抑郁和生活质量水平。
本研究纳入了因经前期症状就诊于一家单院妇产科并使用患者日记诊断为 PMD 的女性。根据诊断，患者分为两组（核心 PMD 和 PME），并分析了她们在首次就诊时心理健康和生活质量问卷的应答情况。
共有 32 名女性被诊断为 PMD（22 名核心 PMD，10 名 PME）。所有 PME 女性的潜在医学疾病均为精神障碍。两组在各种因素方面均无显著差异。在心理健康方面，PME 组的焦虑和抑郁水平高于核心 PMD 组。在生活质量方面，除身体和社会功能外，PME 组在所有领域的得分均低于核心 PMD 组。
因经前期症状就诊的患者中包括许多 PME。与核心 PMD 女性相比，PME 女性更焦虑和抑郁，且其生理和心理领域的生活质量均较低。PME 患者应得到更恰当的诊断和治疗。
