School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC (Toval).
Division of General Obstetrics, Gynecology, and Midwifery, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC (Darivemula).
Am J Obstet Gynecol MFM. 2024 Oct;6(10):101464. doi: 10.1016/j.ajogmf.2024.101464. Epub 2024 Aug 13.
To conduct a systematic review of interventions to improve perinatal outcomes to mitigate pregnancy-related mortality and morbidity in Black birthing people.
We searched 5 databases from 2000 through the final search date of April 5, 2023: Cumulative Index of Nursing and Allied Health Literature Plus with Full Text (EBSCOhost), Embase (Elsevier), PubMed, and Scopus (Elsevier) and ClinicalTrials.gov.
Only quantitative studies were eligible including observational and randomized controlled trials. All participants in selected studies must identify as Black or study results must be stratified by race that includes Black birthing people. The study must (1) measure a perinatal outcome of interest (2) occur in the United States and (3) be written in the English language. Studies were excluded if they were published prior to 2000, not published in the English language, or did not meet the criteria above.
A data extraction template identified intervention type and perinatal outcome. Perinatal outcomes included but were not limited to: cardiovascular disorders, mortality, or preterm delivery. Interventions included: community programs, educational enhancement, individual counseling, medical intervention, or policy. Risk of bias was assessed using the Mixed Method Appraisal Tool. Three investigators assessed studies individually and group consensus was used for a final decision.
From 4,302 unique studies, 41 studies met inclusion criteria. Community programs such as the Supplemental Program for Women, Infants, and Children (WIC) and Healthy Start (n=17, 41.5%) were the most common interventions studied. Individual counseling closely followed (n=15, 36.6%). Medical interventions were not among the more commonly used intervention types (n=9, 21.9%). Most articles focused on preterm delivery (n=28, 68.3%). Few articles studied cardiovascular disorders (n=4, 9.8%) or hemorrhage (n=3, 7.3%). No articles studied pregnancy-related morbidity.
Despite current conversations on Black maternal mortality, there is currently limited literature examining interventions addressing perinatal morbidity and mortality in Black birthing people in the United States. These interventions do not address how to mitigate perinatal outcomes of interest. Patient-centered outcomes research is warranted to better understand as well as to resolve inequities related to Black maternal health. El resumen está disponible en Español al final del artículo.
系统评价改善围产期结局的干预措施,以减轻与妊娠相关的黑人生育者的死亡和发病。
我们从 2000 年到 2023 年 4 月 5 日的最后一次搜索日期,在 5 个数据库中进行了搜索:护理与联合健康文献累积索引加全文(EBSCOhost)、Embase(Elsevier)、PubMed 和 Scopus(Elsevier)以及 ClinicalTrials.gov。
只有定量研究符合条件,包括观察性研究和随机对照试验。所有入选研究的参与者必须自我认定为黑人,或研究结果必须按包括黑人产妇在内的种族分层。研究必须:(1)测量感兴趣的围产期结局;(2)发生在美国;(3)用英语书写。如果研究发表于 2000 年之前、非英文发表或不符合上述标准,则将其排除在外。
数据提取模板确定了干预类型和围产期结局。围产期结局包括但不限于心血管疾病、死亡率或早产。干预措施包括:社区项目、教育强化、个体咨询、医疗干预或政策。使用混合方法评估工具评估偏倚风险。三位研究人员分别评估研究,然后使用小组共识做出最终决定。
从 4302 篇独特的研究中,有 41 篇符合纳入标准。妇女、婴儿和儿童补充计划(WIC)和健康启动等社区项目(n=17,41.5%)是研究最多的干预措施。紧随其后的是个体咨询(n=15,36.6%)。医疗干预措施不是更常用的干预类型之一(n=9,21.9%)。大多数文章侧重于早产(n=28,68.3%)。很少有文章研究心血管疾病(n=4,9.8%)或出血(n=3,7.3%)。没有文章研究与妊娠相关的发病率。
尽管目前正在讨论黑人产妇死亡率问题,但目前有关美国黑人产妇围产期发病率和死亡率的干预措施的文献有限。这些干预措施并没有解决如何改善感兴趣的围产期结局的问题。需要进行以患者为中心的结局研究,以更好地了解和解决与黑人产妇健康有关的不平等问题。