Zahari Nur A'fifah Husna, Farid Durratul Aqwa Mohd, Alauddin Muhammad Syafiq, Said Zulfahmi, Ghazali Mohd Ifwat Mohd, Lee Hao-Ern, Zol Syazwani Mohamad
Faculty of Dentistry, Universiti Sains Islam Malaysia, Kuala Lumpur, Malaysia.
Lecturer, Department of Conservative Dentistry and Prosthodontics, Faculty of Dentistry, Universiti Sains Islam Malaysia, Kuala Lumpur, Malaysia.
J Prosthet Dent. 2024 Dec;132(6):1329.e1-1329.e6. doi: 10.1016/j.prosdent.2024.07.017. Epub 2024 Aug 15.
Current 3-dimensionally (3D) printed denture bases have inadequate strength and durability for long-term use, and milled denture bases generate excessive waste. Addressing these limitations is crucial to advancing prosthetic dentistry, ensuring improved patient outcomes and promoting environmental responsibility.
The purpose of this in vitro study was to incorporate microparticles into a commercially available 3D printed denture base resin and compare its mechanical and biological properties with the conventional polymethyl methacrylate (PMMA) denture base material.
Microparticles were collected from milled zirconia blanks and were blended with a 3D printing denture base resin (NextDent Denture 3D+). The optimal zirconia microparticle content (2%) for blending and printed was determined by using a liquid-crystal display (LCD) 3D printer. The printed specimens were then postrinsed and postpolymerized based on the manufacturer's instructions. Mechanical and biological characterization were carried out in terms of flexural strength, fracture toughness, and fungal adhesion. One-way ANOVA was carried out to analyze the results statistically.
The incorporation of microparticles in the 3D printed denture demonstrated higher mechanical strength (104.77 ±7.60 MPa) compared with conventional heat-polymerized denture base resin (75.15 ±24.41 MPa) (P<.001), but the mechanical strength deteriorated when compared with the unmodified 3D printing resin (122.17 ±11.58 MPa) (P<.001). However, the modified 3D printed denture showed greater antibacterial activity (1184.00 ±243.25 CFU/mL) than the unmodified resin (1486.50 ±103.94 CFU/mL) (P=.045).
The incorporation of microparticles into the 3D printed denture base resin demonstrated the potential to enhance the mechanical and biological properties of the denture base when compared with conventional techniques. However, when compared with the unmodified 3D printed denture base resin, the mechanical properties deteriorated while the biological properties improved.
当前的三维（3D）打印义齿基托长期使用时强度和耐用性不足，而铣削义齿基托会产生过多废料。解决这些局限性对于推动口腔修复学发展、确保改善患者治疗效果以及促进环境责任至关重要。
本体外研究的目的是将微粒加入市售的3D打印义齿基托树脂中，并将其机械性能和生物学性能与传统的聚甲基丙烯酸甲酯（PMMA）义齿基托材料进行比较。
从铣削氧化锆坯料中收集微粒，并与3D打印义齿基托树脂（NextDent Denture 3D+）混合。使用液晶显示器（LCD）3D打印机确定混合和打印的最佳氧化锆微粒含量（2%）。然后根据制造商的说明对打印的试样进行后冲洗和后聚合。从弯曲强度、断裂韧性和真菌粘附方面进行机械性能和生物学特性分析。进行单因素方差分析以对结果进行统计学分析。
与传统热聚合义齿基托树脂（75.15±24.41MPa）相比，3D打印义齿中加入微粒后显示出更高的机械强度（104.77±7.60MPa）（P<0.001），但与未改性的3D打印树脂（122.17±11.58MPa）相比，机械强度有所下降（P<0.001）。然而，改性3D打印义齿比未改性树脂显示出更大的抗菌活性（1184.00±243.25CFU/mL）（1486.50±103.94CFU/mL）（P=0.045）。
与传统技术相比，在3D打印义齿基托树脂中加入微粒显示出增强义齿基托机械性能和生物学性能的潜力，但与未改性的3D打印义齿基托树脂相比，机械性能变差而生物学性能改善。
