[工程化外泌体治疗肺癌的研究进展]
[Research Progress of Engineered Exosomes in the Treatment of Lung Cancer].
作者信息
Yang Wanling, Gu Yan
机构信息
Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China.
出版信息
Zhongguo Fei Ai Za Zhi. 2024 Jul 20;27(7):535-540. doi: 10.3779/j.issn.1009-3419.2024.101.17.
Abstract
The best treatment for non-small cell lung cancer is early surgical treatment, but most lung cancer is diagnosed at an advanced stage. The main treatment methods are drug and radiotherapy. However, drug resistance or no signifi cant effect of the above treatment methods is inevitable. Therefore, more methods are urgently needed for the treatment of lung cancer. Studies have confirmed that engineered exosomes have good clinical application potential in cardiovascular diseases, tumors, tissue regeneration and repair. This paper summarizes the application of engineered exosomes in the treatment of lung cancer at home and abroad. .
摘要
非小细胞肺癌的最佳治疗方法是早期手术治疗，但大多数肺癌在晚期才被诊断出来。主要治疗方法是药物治疗和放射治疗。然而，上述治疗方法不可避免地会出现耐药性或无明显效果。因此，迫切需要更多的肺癌治疗方法。研究证实，工程化外泌体在心血管疾病、肿瘤、组织再生和修复方面具有良好的临床应用潜力。本文综述了工程化外泌体在国内外肺癌治疗中的应用。
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本文引用的文献
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Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications.用于治疗应用的杂交外泌体、类外泌体纳米囊泡和工程化外泌体。
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