Barrantes Murillo Daniel Felipe, Berrocal Alexis, Bell Cynthia, Rissi Daniel R, Craig Linden E, Graham Erin A, Brinker Emily J, Negrão Watanabe Tatiane Terumi
Auburn University, Auburn, AL.
Laboratorio de Patología Veterinaria Histopatovet, Heredia, Costa Rica.
Vet Pathol. 2025 Jan;62(1):31-36. doi: 10.1177/03009858241273238. Epub 2024 Aug 15.
Fibrolipoma is defined as a typical lipoma transected by variable amounts of paucicellular and collagenous fibrous components. Oral and lingual fibrolipomas are well-recognized histological entities in human medicine that are slightly more prevalent in females, occur most commonly after the fourth decade, and arise from the buccal mucosa. The documentation of this neoplasm in the oral cavity is lacking in veterinary medicine. Through a multi-institutional retrospective compilation of cases submitted to diagnostic pathology services, here we describe the clinical and pathologic features of oral fibrolipomas in dogs. A total of 112 cases of oral fibrolipomas in dogs were retrieved. The mean age was 10.1 years (range 2-16 years, ±2.63 years standard deviation), with an average tumor size of 1.7 cm (range 0.2-8 cm, ±1.1 cm standard deviation). The most common location was the tongue (57.1%, 64/112), followed by the buccal mucosa (15.2%, 16/112), sublingual area (8.0%, 9/112), gingiva and lip (4.5%, 5/112 each), and palate (1 case). The anatomical location of oral fibrolipomas only differed significantly among the dog breeds ( < .001) but not among sex, age, anamnesis, or reason for submission. The tumor was most commonly reported in males (69.7%, 78/112), and in 62.5% (70/112) of the cases, the tumor was an incidental finding. Fibrolipoma should be considered a differential diagnosis when considering benign lingual and other oral soft tissue masses in dogs.
纤维脂肪瘤被定义为一种典型的脂肪瘤，其中含有不同数量的少细胞和胶原纤维成分。口腔和舌部纤维脂肪瘤在人类医学中是公认的组织学实体，在女性中略为常见，最常发生在40岁以后，起源于颊黏膜。在兽医学中，口腔内这种肿瘤的文献报道较少。通过对提交给诊断病理服务部门的病例进行多机构回顾性汇总，我们在此描述犬口腔纤维脂肪瘤的临床和病理特征。共检索到112例犬口腔纤维脂肪瘤病例。平均年龄为10.1岁（范围2 - 16岁，标准差±2.63岁），肿瘤平均大小为1.7厘米（范围0.2 - 8厘米，标准差±1.1厘米）。最常见的部位是舌头（57.1%，64/112），其次是颊黏膜（15.2%，16/112）、舌下区域（8.0%，9/112）、牙龈和唇部（各4.5%，5/112）以及上腭（1例）。犬口腔纤维脂肪瘤的解剖位置仅在不同犬种之间存在显著差异（<0.001），但在性别、年龄、病史或提交病例的原因方面没有差异。该肿瘤最常报道于雄性犬（69.7%，78/112），在62.5%（70/112）的病例中，肿瘤是偶然发现的。在考虑犬的良性舌部和其他口腔软组织肿块时，应将纤维脂肪瘤列为鉴别诊断之一。
