de Visscher J G
J Maxillofac Surg. 1982 Aug;10(3):177-81. doi: 10.1016/s0301-0503(82)80036-2.
The clinical and histological characteristics of 19 lipomas and fibrolipomas of the oral cavity are presented. Data on age, sex, location, clinical appearance, duration, recurrence and histological diagnosis are reviewed. The data gave a slightly higher incidence of oral lipomas in comparison with lipomas of the whole body (2.2%), and with benign tumours of the oral cavity (2.4%) than reported in the literature. As with many tumours the aetiology of lipomas remains obscure. It is though that repeated mild trauma may trigger the proliferation of fatty tissue and finally causes a lipoma. In 1971 Hatziotis reviewed the literature from 1945 to 1967 and found 145 cases of intraoral lipomas. The literature up to 1981 has been surveyed and 80 additional cases were found. These 225 oral lipomas and fibrolipomas were reviewed. Sixty-six per cent of the tumours occurred in patients in the fifth to the seventh decade. The male-female ratio for lipomas was 1.5:1, and for fibrolipomas 1:1,3. In most cases the only symptom was a painless, palpable tumour. The time between the initial discovery and removal was on average 4 years and 9 months. The cheek was the most favoured site, followed by the tongue, floor of mouth and buccal sulcus and vestibule equally, lip, palate, gingiva and retromolar area. Surgical excision is the treatment of choice and, as far as is known, recurrence has only once been noticed.
本文介绍了19例口腔脂肪瘤和纤维脂肪瘤的临床及组织学特征。回顾了有关年龄、性别、部位、临床表现、病程、复发情况及组织学诊断的数据。数据显示,口腔脂肪瘤的发病率略高于全身脂肪瘤(2.2%),也高于口腔良性肿瘤(2.4%),这一比例高于文献报道。与许多肿瘤一样,脂肪瘤的病因仍不明确。据认为,反复的轻度创伤可能触发脂肪组织的增生,最终导致脂肪瘤。1971年,哈齐奥蒂斯回顾了1945年至1967年的文献,发现145例口腔内脂肪瘤。对截至1981年的文献进行了调查,又发现了80例。对这225例口腔脂肪瘤和纤维脂肪瘤进行了回顾。66%的肿瘤发生在50至70岁的患者中。脂肪瘤的男女比例为1.5:1,纤维脂肪瘤为1:1.3。在大多数情况下,唯一的症状是可触及的无痛性肿块。从最初发现到切除的平均时间为4年9个月。最常见的部位是颊部,其次是舌部、口底,颊沟和前庭的发生率相同,唇部、腭部、牙龈和磨牙后区较少见。手术切除是首选的治疗方法,据了解,仅发现过1例复发。