Department of Galactophore, The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, China.
Hunan University of Chinese Medicine, Changsha, Hunan, China.
Front Immunol. 2024 Aug 1;15:1431681. doi: 10.3389/fimmu.2024.1431681. eCollection 2024.
The two primary types of non-puerperal mastitis (NPM) are granulomatous lobular mastitis (GLM) and plasma cell mastitis (PCM). Existing research indicates that immune inflammatory response is considered to be the core of the pathogenesis of GLM and PCM, and both innate and adaptive immune responses play an important role in the pathophysiology of PCM and GLM. However, the regulatory balance between various immune cells in these diseases is still unclear. Consequently, we present a comprehensive summary of the immune-related variables and recent advances in GLM and PCM.
两种主要的非产褥期乳腺炎（NPM）是肉芽肿性小叶乳腺炎（GLM）和浆细胞性乳腺炎（PCM）。现有研究表明，免疫炎症反应被认为是 GLM 和 PCM 发病机制的核心，固有和适应性免疫反应在 PCM 和 GLM 的病理生理学中都起着重要作用。然而，这些疾病中各种免疫细胞之间的调节平衡尚不清楚。因此，我们对 GLM 和 PCM 的免疫相关变量和最新进展进行了全面总结。
