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猪器官的流变特性:测量与分数粘弹性模型

Rheological properties of porcine organs: measurements and fractional viscoelastic model.

作者信息

Mishra Aadarsh, Cleveland Robin O

机构信息

Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, United Kingdom.

出版信息

Front Bioeng Biotechnol. 2024 Aug 1;12:1386955. doi: 10.3389/fbioe.2024.1386955. eCollection 2024.

Abstract

The rheological properties of porcine heart, kidney, liver and brain were measured using dynamic oscillatory shear tests over a range of frequencies and shear strains. Frequency sweep tests were performed from 0.1 Hz to a maximum of 9.5 Hz at a shear strain of 0.1%, and strain sweep tests were carried out from 0.01% to 10% at 1 Hz. The effect of pre-compression of samples up to 10% axial strain was considered. The experimental measurements were fit to a Semi-Fractional Kelvin Voight (S-FKV) model. The model was then used to predict the stress relaxation in response to a step strain of 0.1%. The prediction was compared to experimental relaxation data for the porcine organ samples, and the results agreed to within 30%. In conclusion, this study measured the rheological properties of porcine organs and used a fractional viscoelastic model to describe the response in frequency and time domain.

摘要

使用动态振荡剪切试验在一系列频率和剪切应变范围内测量了猪心脏、肾脏、肝脏和大脑的流变特性。频率扫描试验在0.1%的剪切应变下从0.1Hz进行到最大9.5Hz,应变扫描试验在1Hz下从0.01%进行到10%。考虑了样品预压缩至10%轴向应变的影响。将实验测量结果拟合到半分数开尔文-沃伊特(S-FKV)模型。然后使用该模型预测0.1%阶跃应变下的应力松弛。将该预测结果与猪器官样品的实验松弛数据进行比较,结果在30%以内相符。总之,本研究测量了猪器官的流变特性,并使用分数粘弹性模型来描述频域和时域中的响应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8911/11324450/597519aa42f6/fbioe-12-1386955-g001.jpg

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