Filice C, Maserati R, Brunetti E, Minoli L, Suter F
Biol Res Pregnancy Perinatol. 1985;6(3):112-3.
Since its early diagnostic application in the study of pregnancy, ultrasonography (US) has been widely employed in the detection of fetal malformations. Head abnormalities, recognized through the evaluation of brain and skull structures, accounted for the majority of these observations. We report here on a case of holoprosencephaly, a rare malformation (incidence is around 1/16,000 live births according to Roach et al. [1975]) diagnosed and monitored up to delivery by multiple US examinations.
自超声检查（US）早期用于妊娠研究的诊断以来，它已被广泛应用于胎儿畸形的检测。通过评估脑和颅骨结构识别出的头部异常占这些观察结果的大多数。我们在此报告一例全前脑畸形病例，这是一种罕见的畸形（根据Roach等人[1975年]的数据，发病率约为1/16,000活产），通过多次超声检查进行诊断并监测至分娩。
