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小儿食管颗粒细胞瘤的成功内镜下黏膜下剥离术:一例报告及治疗见解

Successful endoscopic submucosal dissection of an esophageal granular cell tumor in a pediatric patient: A case report and a therapeutic insight.

作者信息

Dogom Sara Al, Thongpiya Jerapas, Elmassry Marawan, Feist Mark, Sharma Meenu, Rateb George

机构信息

Department of Pediatrics Texas Tech University Health Sciences Center Lubbock Texas USA.

Department of Internal Medicine Texas Tech University Health Sciences Center Lubbock Texas USA.

出版信息

JPGN Rep. 2024 Jul 4;5(3):384-388. doi: 10.1002/jpr3.12106. eCollection 2024 Aug.

Abstract

Esophageal granular cell tumors (GCTs) are rare mesenchymal neoplasms that originate from the Schwann cells of the neural sheath in the esophageal wall. Esophageal GCTs represent approximately 2% of all GCTs. Most cases of esophageal GCT occur in adults with few cases reported in pediatric patients. Although typically benign, these tumors can occasionally exhibit malignant behavior, necessitating timely and appropriate intervention. Traditionally, surgical resection was considered for treatment, nonetheless, considering the invasive nature of such interventions, endoscopic approaches have been developed for diagnosis and treatment. Endoscopic approaches have been shown to lead to serious complications at times, such as incomplete resection or perforation. Here, we present a successful application of endoscopic submucosal dissection in the treatment of an adolescent female patient with esophageal GCT which was discovered during her prior esophagogastroduodenoscopy for vomiting.

摘要

食管颗粒细胞瘤(GCTs)是一种罕见的间质性肿瘤,起源于食管壁神经鞘的施万细胞。食管GCTs约占所有GCTs的2%。大多数食管GCTs病例发生在成人中,儿科患者中报道的病例较少。虽然这些肿瘤通常是良性的,但偶尔也会表现出恶性行为,因此需要及时和适当的干预。传统上,手术切除被认为是治疗方法,然而,考虑到此类干预的侵入性,已经开发出内镜方法用于诊断和治疗。内镜方法有时已被证明会导致严重并发症,如切除不完全或穿孔。在此,我们展示了内镜黏膜下剥离术在一名青少年女性食管GCT患者治疗中的成功应用,该肿瘤是在她之前因呕吐进行的食管胃十二指肠镜检查中发现的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd81/11322035/aa0a883c3d2a/JPR3-5-384-g002.jpg

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