美国儿科疟疾患者青蒿琥酯治疗后迟发性溶血。
Post-Artesunate Delayed Hemolysis in Pediatric Malaria Patients in the United States.
机构信息
Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
出版信息
J Pediatric Infect Dis Soc. 2024 Nov 4;13(10):533-536. doi: 10.1093/jpids/piae080.
Post-artesunate delayed hemolysis (PADH) occurred in 6 of 24 children treated with artesunate for severe malaria in the United States; however, severe hemolysis requiring hospitalization or transfusion was rare. In children in the United States treated with artesunate, counseling, and symptom monitoring may be preferred to weekly laboratory surveillance for PADH.
美国使用青蒿琥酯治疗重症疟疾的 24 名儿童中有 6 名发生青蒿琥酯治疗后延迟性溶血（PADH）；然而，需要住院或输血的严重溶血则较为少见。对于使用青蒿琥酯治疗的美国儿童，建议采取咨询和症状监测，而不是每周进行实验室监测来预防 PADH。
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